Traditional Chinese medicine composition for treating pancreatic cancer and preparation method thereof

A technology of composition and traditional Chinese medicine, which is applied in the direction of drug combination, medical formula, active ingredients of hydroxyl compounds, etc., can solve the problems of misdiagnosis and mistreatment, poor treatment effect of advanced pancreatic cancer, etc., to reduce tumors, enhance body immunity, relieve painful effect

Inactive Publication Date: 2012-11-21
史德功
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The early symptoms of pancreatic cancer are not typical, and often manifest as symptoms similar to those of other organ lesions, leading to some symptomatic patients being misdiagnosed and mistreated. Most patients diagnosed with pancreatic cancer already have distant metastasis or signs of distant metastasis Advanced pancreatic cancer, but Western medicine is not effective in treating advanced pancreatic cancer. It can only be surgery, radiotherapy, chemotherapy, cutting and cutting until the end of life. Patients have been in pain, and less than 20% of patients have radical surgery hope

Method used

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Examples

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Effect test

preparation example Construction

[0069] When the dosage form of the Chinese medicine composition is buccal tablet, its preparation method comprises the following steps:

[0070] In the first step, mix the sarcocarpus, black snake, barbata, lobelia, hedyotis diffusa, calamus, and trichosanthes in the stated proportion, and use 4 to 6 times the mass of the obtained mixture with alcohol Dissolve in ethanol with a concentration of 90% to 95%, extract after heating and reflux for 2 to 4 hours, filter, and dissolve the filter residue with ethanol with an alcohol concentration of 85% to 95% that is 2 to 4 times the mass of the obtained mixture, and heat again After refluxing for 1-2 hours, extract, filter, and combine the two filtrates, recover ethanol under reduced pressure and concentrate to a concentration of 0.8-1.2 g crude drug / mL. Elute with deionized water or distilled water twice the volume of the resin column, and then elute with ethanol with an alcohol concentration of 3 times the volume of the resin colum...

Embodiment 1

[0087] Embodiment 1: buccal tablet prepared by the present invention

[0088] 28g syringa, 12g black snake, 15g barbata, 15g lobelia, 22g diffusa, dandelion 35g, viola 32g, Patrinia 23g, honeysuckle 40g, forsythia 18g, licorice 25g, light bamboo leaves 20g, Capillary Artemisia 15g, Codonopsis 26g, Gardenia 15g, Rhubarb 15g, Coix Seed 25g, Red Rattan 20g, Black Plum 30g, Borneol 30g, Desmodium 20g, Polyporus 30g, Red Cardamom 35g, Turmeric 20g, Shichangpu 10g, Lycium barbarum 35g, Shegan 25g, Radix Paeoniae Rubra 20g and TCS 35g.

[0089] Its preparation method comprises the following steps:

[0090] In the first step, mix sargassum, black snake, barbata, lobelia, hedyotis diffusa, calamus, and trichosanthes in the stated ratio, and use 95% alcohol concentration 5 times the mass of the obtained mixture % of ethanol was dissolved, heated and refluxed for 3 hours, extracted, filtered, and the filter residue was dissolved in ethanol with an alcohol concentration of 90% which was...

Embodiment 2

[0094] The capsule prepared by embodiment 2 the present invention

[0095] Scutellaria 25g, Snake 10g, Scutellaria barbata 13g, Lobelia 18g, Hedyotis diffusa 23g, Dandelion 40g, Viola 35g, Patrinia 20g, Honeysuckle 35g, Forsythia 15g, Licorice 30g, Bamboo leaves 22g, Capillary Artemisiae 18g, Codonopsis 28g, Gardenia 16g, Rhubarb 12g, Coix Seed 20g, Red Rattan 16g, Black Plum 25g, Borneol 28g, Desmodium 22g, Polyporus 32g, Red Cardamom 30g, Turmeric 25g, Shichangpu 11g, Lycium barbarum 30g, Shegan 22g, Radix Paeoniae Rubra 23g, Trichosanthes 32g, Poria 18g, Ginseng 30g and Atractylodes macrocephala 25g.

[0096] Its preparation method comprises the following steps:

[0097] In the first step, the raw medicinal materials are mixed in proportion, put into a casserole and fried for 35 minutes, crushed into fine powder with a pulverizer, and sieved into a 120-mesh powder;

[0098] In the second step, add ethanol with an alcohol concentration of 80% that is 4 times the mass of th...

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Abstract

The invention provides a traditional Chinese medicine composition for treating the pancreatic cancer and a preparation method of the traditional Chinese medicine composition. The medicinal raw materials of the traditional Chinese medicine composition are as follows: herba sarcandrae, zaocys dhumnade, scutellariae barbatae, Chinese lobelia, oldenlandia diffusa, taraxacum mongolicum, herba violae, herba patriniae, flos lonicerae, fructus forsythiae, radix glycyrrhiza, herba lophatheri, herba artemisiae scopariae, codonopsis pilosula, fructus gardeniae, rheum officinale, semen coicis, caulis sargentodoxae, fructus mume, borneol, christina loosestrife herb, polyporus umbellatus, fructus galangae, radix curcumae longae, rhizoma acori graminei, fructus lycii, rhizoma belamcandae, radix paeoniae rubra and radix trichosanthis. The traditional Chinese medicine composition provided by the invention can be separately utilized or matched up with radiotherapy and chemotherapy, and have the effects of reducing the lumps in a short period and effectively controlling the metastatic spread of cancer cells; and moreover, the traditional Chinese medicine composition is capable of strengthening the immunologic function of the organisms so as to achieve the aims of inhibiting the growth of the cancer cells, being free of side effects simultaneously, enhancing the immunity of the organisms while treating and resisting the cancers, alleviating the pain of the patients, stabilizing the state of the illness, prolonging the life cycle and increasing the proportion of clinically treating the patients.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating pancreatic cancer and a preparation method thereof. Background technique [0002] Pancreatic cancer is rare among malignant tumors of the digestive tract. It is more common in the age of 40 to 60, and more men than women. Pancreatic cancer mostly occurs in the head of the pancreas, and only a few occur in the body and tail of the pancreas. Pancreatic cancer has different clinical symptoms due to the location of the cancer and the difference in the course of the disease. Abdominal pain is the earliest symptom, which is more common in the body and tail of the pancreas, and mostly radiates to the lower back. During the development of the disease, there may be jaundice, and abdominal mass and fever may appear in the late stage. The supraclavicular lymph nodes are the most common metastatic sites. Modern m...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P1/18A61P35/00A61K35/58A61K31/045A61K35/583
Inventor 郑美芳毕延萍
Owner 史德功
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