Rhizoma cyperi four-drug decoction transdermal patch and preparation method thereof

A technology of transdermal patch and Siwu decoction, applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve the problems of first-pass effect gastrointestinal tract damage, low bioavailability, etc. The effect of improved bioavailability and less contamination of clothes
CN102940754AActive Publication Date: 2013-02-27NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
Publication Date
2013-02-27

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Abstract

The invention discloses a rhizoma cyperi four-drug decoction transdermal patch and a preparation method of the rhizoma cyperi four-drug decoction transdermal patch. The patch comprises a heating bag, a back lining layer fixed on the heating bag, a medicine-containing base material layer fixed on the back lining layer and an anti-sticking layer covering the medicine-containing base material layer, wherein the medicine-containing base material layer comprises 30-70 parts of hydrogel base material, 10-50 parts of rhizoma cyperi four-drug decoction extracting part and 10-40 parts of a transdermal accelerant. The transdermal patch disclosed by the invention has scientific and reasonable component proportions and great medicine loading amount; and an organic solvent does not need to be added in a preparation process so that the patch has no skin irritation and sensitization. An experiment result shows that the transdermal patch has the very good effect of treating primary dysmenorrheal; the biological utilization rate is high; the transdermal patch can be continuously released at a constant speed and is good for keeping a stable blood medicine concentration; the pesticide effect time is long; and a preparation process of the patch has strong operability and can realize industrial production.
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Description

Technical field:

[0001] The invention relates to a patch, in particular to a Xiangfu Siwutang transdermal patch capable of preventing and treating dysmenorrhea and a preparation method thereof. Background technique

[0002] Dysmenorrhea refers to the cramping pain in the lower abdomen that women experience before and after menstruation. In severe cases, it may be accompanied by symptoms such as headache, nausea, vomiting, abdominal distension, backache, and leg pain. At present, it is clinically divided into two types: primary dysmenorrhea and secondary dysmenorrhea. Epidemiological studies have shown that dysmenorrhea is the most common disease in gynecology at present, with an incidence rate between 20% and 90%, and it is a common cause that affects women's normal work and quality of life.

[0003] According to traditional Chinese medicine, if any reason causes chongren qi and blood to be blocked, uterine blood stasis, resulting in blocked meridians, or blood not returnin...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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