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Sleep improvement composition and its preparation method

A technology for improving sleep and composition, applied in the field of sleep improving composition and its preparation and preparation, capable of solving problems such as epileptic seizures, hallucinations, and behavioral disorders, and achieving the effects of soothing emotions, calming emotions, and improving sleep

Active Publication Date: 2014-12-10
BEIJING COMPETITOR SPORTS SCI & TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Moreover, sleeping pills such as diazepam are mainly transformed by the human liver and eliminated by the kidneys, so overdose will increase the burden on liver and kidney functions
Some people who take a large amount of drugs for a long time, if they suddenly reduce the dose or stop taking them, they will also be accompanied by nausea or vomiting, coarse tremors in the hands, tongue and eyelids, leading to behavioral disturbances, hallucinations, and even seizures

Method used

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  • Sleep improvement composition and its preparation method
  • Sleep improvement composition and its preparation method

Examples

Experimental program
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Effect test

Embodiment 1

[0024] Embodiment 1: Capsules

[0025] 1. Prescription (weight): 200g gamma-aminobutyric acid powder, 50g jujube seed extract, 84g magnesium oxide (containing 60% magnesium), vitamin B 6 10g, microcrystalline cellulose 440g, magnesium stearate 16g, prepare 4000 grains.

[0026] 2. Preparation method:

[0027] 1) Weigh gamma-aminobutyric acid and Jujube seed extract according to the prescription, pass through a 40-mesh sieve respectively, and set aside;

[0028] 2) Weigh the microcrystalline cellulose and magnesium stearate according to the prescription, mix the above-mentioned raw and auxiliary materials uniformly according to the method of equal addition, pour them into a capsule filling mold, fill the capsules, polish and pack them separately.

[0029] 3. Specifications: Each capsule contains 0.1g of gamma-aminobutyric acid, 0.025g of jujube seed extract, 0.025g of magnesium, and vitamin B 6 0.005g.

[0030] 4. Dosage: Take 2 capsules per day

Embodiment 2

[0031] Embodiment 2: tablet

[0032] 1. Prescription (weight): 2500g of 20-type γ-aminobutyric acid, 2000g of jujube seed extract, 5000g of magnesium oxide (containing 60% magnesium), vitamin B 6 5g, 395g of lactose, 100g of magnesium stearate, and prepare 10000 tablets.

[0033] 2. Preparation method:

[0034] 1) Weigh type 20 gamma-aminobutyric acid, Chinese date seed extract, magnesium oxide, and vitamin B according to the prescription 6 , lactose, and magnesium stearate are passed through an 80-mesh sieve respectively, and set aside;

[0035] 2) Mix the above-mentioned raw and auxiliary materials (except magnesium stearate) uniformly according to the method of equal addition, use water as a binder, and make a soft material, and pass the above-mentioned soft material through a 14-mesh sieve oscillating granulator to make granules , put the granules into a multi-functional boiling dryer, boil and dry at 50°C for about 40 minutes, control the water content of the granules ...

Embodiment 3

[0038] Embodiment 3: powder

[0039] 1. Prescription (weight): 800g of 20-type γ-aminobutyric acid, 80g of jujube seed extract, 2500g of magnesium lactate (containing 8% magnesium), vitamin B 6 1 g, 3619 g of isomalt, and 3000 g of mannitol, and prepare 1000 bags.

[0040] 2. Preparation method:

[0041] 1) Type 20 gamma-aminobutyric acid, jujube seed extract, magnesium lactate, vitamin B according to the prescription 6 Pass through a 40-mesh sieve respectively, and set aside;

[0042] 2) Mix the above-mentioned raw and auxiliary materials evenly according to the method of equal volume addition, and pack them separately.

[0043] 3. Specifications: Each bag contains 0.16g of γ-aminobutyric acid, 0.08g of jujube seed extract, 0.2g of magnesium, and vitamin B 6 0.001g.

[0044] 4. Dosage: Take 1 bag per day.

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Abstract

The invention provides a sleep improvement composition. The sleep improvement composition is composed of gamma-aminobutyric acid, a spine date seed extract, magnesium and vitamin B6. The invention also provides a preparation of the sleep improvement composition and a preparation method of the sleep improvement composition. The sleep improvement composition contains no hypnotic components, and can effectively calm motion and improve the sleep for high-pressure populations and poor sleepers.

Description

technical field [0001] The invention relates to a composition for improving sleep, in particular to a composition composed of gamma-aminobutyric acid, jujube seed extract, magnesium, vitamin B 6 Composition for improving sleep, formulation and preparation method thereof. Background technique [0002] The Global Sleep and Health Program sponsored by the International Mental Health Organization launched a global activity in 2001 - designating March 21 of each year, the first day of spring, as "World Sleep Day". One-third of a person's life is spent in sleep, and five days without sleep will affect people's survival. It can be seen that sleep is one of the important physiological needs of people. Sleep is an essential process of life, an important part of the body's recovery, integration and memory consolidation, and an indispensable part of health. According to the World Health Organization survey, 27% of people have sleep problems. [0003] Long-term use of sleeping pills ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/725A61P25/20A61K31/4415A61K33/06A61K31/197A61K31/191A61K33/08A61K33/10A61K31/19A61K31/198
Inventor 白厚增焦颖杨则宜朱连君宋贵林
Owner BEIJING COMPETITOR SPORTS SCI & TECH
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