Molecular biology method for predicating endurance potentials of excellent ice-snow sportsmen
An athlete, excellent technique, applied in interdisciplinary fields
Inactive Publication Date: 2013-06-19
HARBIN INST OF PHYSICAL EDUCATION
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Problems solved by technology
However, studies have also confirmed that there is significant variability in ACE levels between individuals, with differences of up to 5-fold
Method used
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Embodiment
[0011] Example: ACE gene I / D (kininase II gene insertion / deletion type) polymorphism analysis
[0012] research object
[0013] The research objects are mainly divided into two groups, the elite ice and snow athlete group and the ordinary people group. The ordinary people group mainly selects the local people who are of the same age as the outstanding athletes this time, strictly in accordance with the principle of random sampling, and none of them have a history of professional sports training.
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Abstract
The invention discloses a molecular biology method for predicating the endurance potentials of excellent ice-snow sportsmen, which can be used for inquiring the relationship between the I/D (kininase II gene insertion/deletion) polymorphisms of ACE (angiotensin-converting enzyme) and the endurance potentials of the excellent ice-snow sportsmen. Lots of research results indicate that the genetic I/D polymorphisms are associated with the aerobic endurance of the sportsmen, are the key factors for judging the aerobic endurance quality of a human body, and affect the optimal level of the aerobic endurance quality of a human body and the sensitivity of a human body for endurance training; and the genes mainly affect the cardio-pulmonary function of a human body, and thus affecting the aerobic endurance quality of a human body. In consideration that the ACE genes are related to the aerobic endurance of movements, researches for the distribution of the genes in the excellent ice-snow sportsmen by applying the molecular biology method have important theoretical significance for determining the relevance between the genes and endurance-type ice-snow sports, and lay the foundation of future molecular selection by applying the molecular biology method.
Description
technical field [0001] The present invention relates to a molecular biological method for predicting the endurance potential of excellent ice and snow athletes, specifically by analyzing the polymorphism of ACE (Angiotensin-converting enzyme) I / D (kininase II gene insertion / deletion type), thereby Learn how polymorphisms in the ACE gene affect the gift of exceptional endurance. This invention belongs to the interdisciplinary field of basic life science, human genetic resources, molecular biology and sports science. Background technique [0002] ACE is a 20-peptide single-chain acid glycoprotein, which is a zinc-containing metallohydrolase, and its system name is peptidyl-dipeptide hydrolase or kininase II. ACE widely exists in various tissues of the body, mainly distributed in vascular endothelial cells (especially in pulmonary circulation), renal epithelial cells, etc. Bradykinin, a natural substrate of ACE, inhibits its biological activity by cleaving two hydroxyl-termin...
Claims
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Patent Type & Authority Applications(China)
IPC IPC(8): C12Q1/68
Inventor 刘石武大伟谭睿裴沛张文秀关伟军
Owner HARBIN INST OF PHYSICAL EDUCATION
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