Isolated organ constant pressure perfusion device
An isolated organ and perfusion technology, which is applied in the fields of medical perfusion devices and isolated organ constant pressure perfusion devices, can solve the problems of complex structure, mercury ejection or inversion, and achieves simple structure, simple manufacturing method and obvious constant pressure effect. Effect
Inactive Publication Date: 2014-11-05
XI AN JIAOTONG UNIV
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Problems solved by technology
Adjust the gas input flow rate so that all the mercury in the thin tube 3 is removed, and the length of the thin tube 3 deep into the mercury is the perfusion pressure. The structure of this device is complicated, and mercury is prone to ejection or backflow during operation, so it has not been popularized.
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Embodiment Construction
[0022] The present invention will be further described in detail below in conjunction with specific drawings and embodiments, which are explanations rather than limitations of the present invention.
[0023] see figure 1 , the isolated organ constant pressure perfusion device of the present invention comprises a liquid storage bottle 3, an air inlet pipe 1 and an air outlet pipe 2 are arranged at the mouth of the liquid storage bottle 3, and an air supply device is connected on the air inlet pipe 1 for passing in Oxygen or O for isolated organs 2 -CO 2 Mixed gas, adjust the air intake to 1 to 2 bubbles / min; there is also a nutrient solution outflow tube 6 on the side wall at the bottom of the liquid storage bottle 3, and a tray for carrying the liquid storage bottle 3 is provided under the liquid storage bottle 3 4. An elastic device is connected to the bottom of the tray 4, the elastic device includes a pressure shaft 5, the top of the pressure shaft 5 is fixedly connected ...
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The invention discloses an isolated organ constant pressure perfusion device belonging to the field of medical equipment. The isolated organ constant pressure perfusion device comprises a liquid storage bottle, wherein a bottle opening of the liquid storage bottle is provided with an air inlet pipe and an air outlet pipe, the bottom sidewall of the liquid storage bottle is further provided with a nutrient solution flow-out pipe, a tray for supporting the liquid storage bottle is arranged under the liquid storage bottle, an elastic device is connected under the tray, and a support frame is arranged under the elastic device. For the constant pressure perfusion device provided by the invention, the volume of the liquid storage bottle can be designed as needed, the high-volume liquid storage bottle can effectively reduce the perfusate adding times in the use process, and thus, perfusion pressure can be kept constant; meanwhile, the air inlet pipe is arranged above the liquid storage bottle containing the nutrition solution, needed oxygen or mixed gas can be introduced, the problem of perfusion for the isolated organ of mammal is solved, by performance testing, the rate of change of the perfusion pressure of the device provided by the invention in the whole test process is less than 0.17%, and the constant pressure effect is obvious.
Description
technical field [0001] The invention belongs to the field of medical equipment, and relates to a medical perfusion device, in particular to a constant-pressure perfusion device for isolated organs. Background technique [0002] Perfusion of isolated organs is a basic experimental method commonly used in medical teaching, scientific research, and clinical practice. Nutrients are continuously perfused through the vascular network in the organ to maintain the survival of the isolated organ and maintain its physiological functions. Each organ requires a relatively stable perfusion Maintaining a stable perfusion pressure can reduce organ and tissue damage, especially in the process of donor organ transportation and surgical preparation before kidney transplantation, heart transplantation, and liver transplantation; Perfusion is a good method to study the action and mechanism of vasoactive substances including drugs, and it is also a common method to explore the physiological and ...
Claims
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IPC IPC(8): A01N1/02
Inventor 刘书勤臧伟进
Owner XI AN JIAOTONG UNIV