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Donkey-hide-gelatin-containing instant granules and preparation method thereof

A technology of instant granules and donkey-hide gelatin, which is applied to medical preparations containing active ingredients, medical preparations with non-active ingredients, and pharmaceutical formulas, etc. It can solve the problem of instant dissolving of donkey-hide gelatin compound products and achieve easy quality Control, particle uniformity, and the effect of ensuring hygienic conditions

Inactive Publication Date: 2013-09-11
刘贺虎
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current various formulas and processes cannot well solve the instant problem of donkey-hide gelatin compound products.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Weigh 45 kg donkey-hide gelatin, 18 kg jujube, 8 kg hawthorn, 8 kg schisandra, 8 kg licorice, 1.5 kg Tween-40, 0.4 kg sodium lauryl sulfate, 0.6 kg sucrose monofatty acid ester and 0.08 kg sweetener; The specific process operation steps are as follows:

[0021] (1) Get the above-mentioned red dates, hawthorn, schisandra, 420 kg of water and soak for 2 hours, decoct for 2 hours, filter to get the dregs of medicine and the first decoction liquid, add 420 kg of dregs of water to decoct for 2 hours, filter , to obtain the second decoction, merge the decoction for the first time and the decoction for the second time, steam-heat the decoction after merging in an open stainless steel container, and concentrate it into a clear paste with a relative density of 1.1;

[0022] (2) dissolving Tween-40, sodium lauryl sulfate, sucrose monofatty acid ester in warm water at 75°C in parts by weight of 3 kg to obtain a compound emulsifier solution;

[0023] (3) Add donkey-hide gelatin an...

Embodiment 2

[0027] Weigh 55 kg donkey-hide gelatin, 22 kg red dates, 12 kg hawthorn, 12 kg schisandra, 12 kg licorice, 1.5 kg Tween-40, 0.6 kg sodium lauryl sulfate, 0.6 kg sucrose monofatty acid ester and 0.12 kg sweetener; The specific process operation steps are as follows:

[0028] (1) Get the above-mentioned red dates, hawthorn, schisandra, 580 kg of water and soak for 2 hours, decoct for 2 hours, filter to obtain the dregs of medicine and the first decoction liquid, add 580 kg of dregs of water to decoct for 2 hours, filter , to obtain the second decoction, merge the decoction for the first time and the decoction for the second time, steam-heat the decoction after merging in an open stainless steel container, and concentrate it into a clear paste with a relative density of 1.1;

[0029] (2) Dissolve Tween-40, sodium lauryl sulfate, sucrose monofatty acid ester, and 3.5 kg of warm water at 60°C to obtain a compound emulsifier solution;

[0030] (3) Add donkey-hide gelatin and sweete...

Embodiment 3

[0034] Weigh 50 kg of donkey-hide gelatin, 20 kg of red dates, 10 kg of hawthorn, 10 parts of schisandra, 10 kg of licorice, 1.2 kg of Tween-40, 0.4 kg of sodium lauryl sulfate, 0.6 kg of sucrose monofatty acid ester and 0.1 kg of sweetener; The specific process operation steps are as follows:

[0035] (1) Get the above-mentioned red dates, hawthorn, schisandra, 500 kg of water and soak for 2 hours, decoct for 2 hours, filter to obtain the dregs of medicine and the first decoction liquid, add 500 kg of dregs of water to decoct for 2 hours, filter , to obtain the second decoction, merge the decoction for the first time and the decoction for the second time, steam-heat the decoction after merging in an open stainless steel container, and concentrate it into a clear paste with a relative density of 1.1;

[0036] (2) Dissolve Tween-40, sodium lauryl sulfate, sucrose monofatty acid ester, and 3.5 kg of warm water at 70°C to obtain a compound emulsifier solution;

[0037] (3) Heat ...

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Abstract

The invention discloses donkey-hide-gelatin-containing instant granules and a preparation method thereof. The instant granules are prepared from the following components (including raw materials and adjuvants) in parts by weight: 45-55 parts of donkey-hide gelatin, 18-22 parts of red date, 8-12 parts of hawthorn, 8-12 parts of Chinese magnoliavine fruit, 8-12 parts of licorice, 1.0-1.5 parts of tween-40, 0.2-0.6 part of sodium lauryl sulfate, 0.4-0.8 part of mono-fatty acid ester of sucrose and 0.08-0.12 part of sweetening agent. The preparation method includes the following steps of: extracting concentrated juice of red date, hawthorn, Chinese magnoliavine fruit and licorice, adding donkey-hide gelatin and a sweetening agent solution, then mixing with a composite emulsifying agent prepared from tween-40, sodium lauryl sulfate, and mono-fatty acid ester of sucrose, carrying out homogenous emulsification on the mixture, and pelletizing by using a spray drying pelletizing method to obtain the instant granules. The donkey-hide-gelatin-containing instant granules are short in production cycle, uniform in granules, and good in particle solubility.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation of donkey-hide gelatin and a preparation method thereof, in particular to an instant granule containing donkey-hide gelatin and a preparation method thereof. Background technique [0002] Donkey-hide gelatin has been used for more than 2,000 years. Donkey-hide gelatin is an important medicine for nourishing the lungs, and the lungs are the source of blood. Tonifying the lungs can fundamentally solve the problem of insufficient blood source, and can receive a good effect of nourishing qi and blood. It has always been hailed as "blood-enriching holy medicine" and "nourishing national treasure", and together with ginseng and pilose antler, it is known as "three treasures of traditional Chinese medicine". It is collagen extracted from donkey skin. Donkey-hide gelatin is a traditional Chinese medicine. Traditional donkey-hide gelatin is in the form of flakes. It must be smashed before takin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/79A61K36/734A61K47/26A61K47/10A61K9/16A61P1/14
Inventor 刘贺虎
Owner 刘贺虎
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