Compound fructus forsythiae-radix bupleuri oil nanoemulsion and preparation method

Abstract

A compound nanoemulsion of fructus forsythiae and radix bupleuri oil, having a droplet diameter of between 10 nm and 100 nm, and prepared from raw materials in the following percentage by weight: 12.00%-28.00% of a surfactant, 15.00%-30.00% of a cosurfactant, 3.00%-8.00% of oil, 0.10%-5.00% of fructus forsythiae oil, 0.10%-5.00% of radix bupleuri oil, 0.01%-0.05% of vitamin C, 0.01%-0.05% of vitamin B1, and 20.00%-68.40% of distilled water, the total percentage by weight of all the raw materials being 100%.

Description

technical field

[0001] The invention belongs to the field of medicine and relates to a compound forsythia-bupleurum oil nanoemulsion preparation, in particular to a transparent and stable compound forsythia-bupleurum oil nanoemulsion preparation. Background technique

[0002] Forsythia is a traditional Chinese medicine for clearing heat and detoxifying. Forsythia has antibacterial, cardiotonic, diuretic, and antiemetic effects. The main components of the volatile oil of Forsythia are B-pinene, A-pinene and so on. Forsythia volatile oil has antibacterial and antiviral effects, and has obvious inhibitory effects on Staphylococcus aureus, Diplococcus pneumoniae and Candida albicans. Bupleurum oil is yellow-brown to brown volatile essential oil, disperses and reduces fever, raises yang and soothes the liver. For cold and fever, alternating cold and heat, malaria, stagnation of Qi due to depression of the liver, distending pain in the chest and hypochondriac. At present, the m...