Method for preparing eight-treasure granules

Abstract

The invention provides a method for preparing eight-treasure granules. The method comprises the following steps: eight medical materials such as radix codonopsis and bighead atractylodes rhizomes are prepared into Chinese herbal pieces as requested; the angelica sinensis, the ligusticum wallichii and the roasted bighead atractylodes rhizomes are extracted through ethanol reflux after being mixed and ethanol is recovered; the dregs of the decoctions of the angelica sinensis, the ligusticum wallichii and the roasted bighead atrac tylodes rhizome are added with water and then are decocted, wherein the dregs are continuously extracted through the ethanol at a low temperature; the remaining five Chinese herbal pieces such as the radix codonopsis, the Indian buead, the prepared rehmannia roots and the honey-fried licorice roots are added with water and then are decocted; the extracted solutions are mixed and then are concentrated into extractum with a hot test density of 1.08 to 1.20; the extractum is added with ethanol for ethanol precipitation and stilly placed; the supernatant are taken away, the ethanol is recovered, then the solution is concentrated into extractum with a hot test density 1.35-1.38; the extractum is added with auxiliary materials to be made into sugary granules and sugarless granules. According to the method, drug effective ingredients are reserved to the maximum extent; the quantity of the extractum extracted from the eight treasures are remarkably reduced; the problems that in the actual production process, prepared agents are difficult to form and the original technology is susceptible to moisture absorption and caking are solved, so that the method is suitable for industrial production and enables the quality of the drug more stable.

Description

technical field [0001] The invention relates to a preparation method of a Chinese patent medicine, in particular to a preparation method of Bazhen Granules. Background technique [0002] Bazhen granule is recorded in the first part of the "Chinese Pharmacopoeia" 2010 edition. It is composed of Codonopsis pilosula, fried Atractylodes macrocephala, Poria cocos, roasted licorice, angelica, fried white peony root, Chuanxiong, and rehmannia glutinosa. Bazhen granule has the function of invigorating qi and blood, and is used to treat deficiency of both qi and blood, pale complexion, loss of appetite, weakness of limbs, and menorrhagia. Bazhen granule is made from the compatibility of eight traditional Chinese medicines, and the prescription volume is relatively large. The content in the drug is relatively large, and the proportion of excipients is small. It is easy to make preparations difficult to form, or it is easy to absorb moisture and agglomerate, causing problems such as e...

AI Technical Summary

Problems solved by technology

Bazhen granules are made from the compatibility of eight traditional Chinese medicines, and the prescription volume is relatively large. The content in the drug is relatively large, and the proportion of excipients is relatively small. It is easy to make preparations difficult to form, or it is easy to absorb moisture and agglomerate, causing problems such as excessive moisture and unqualified properties, which will make the product quality unqualified and affect the industrial production of drugs. It is difficult to satisfy doctors. and patient needs

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