Natural pharmaceutical composition and preparation method thereof

A technology of natural medicine and composition, applied in the direction of drug combination, pharmaceutical formula, antineoplastic drugs, etc.

Inactive Publication Date: 2013-11-20
石强
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In recent years, with the advent and popularization of chemotherapy drugs such as 5-fluorouracil, taxanes, hydroxycamptothecin, irinotecan, Xeloda, etc., the incidence of chemotherapy-related diarrhea has increased year by year. Treatment can easily lead to dehydration, malnutrition, serum electrolyte disorder, acid-base balance disorder, etc., which not only bring great disadvantages to the recovery of the body, but also bring certain difficulties to periodic chemotherapy. Effective treatment has become an important part of the overall treatment of cancer patients
[0003]Chemotherapy-associated diarrhea, in terms of its clinical manifestations, belongs to the category of "diarrhea" in traditional Chinese medicine. The research on diarrhea in traditional Chinese medicine is remarkable, but at present There is no Chinese patent medicine that can relieve diarrhea and increase efficacy against cancer chemotherapy

Method used

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  • Natural pharmaceutical composition and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment approach

[0035] The first step: preparation of various extracts

[0036] (1) Preparation of concentrated extract of Piper longum clove decoction

[0037] According to the compatibility ratio of 1-4:1, take longum longum and cloves, soak in distilled water, heat and decoct, filter, add distilled water to the dregs, soak, decoct, and filter in the same way, mix the two filtrates, heat and concentrate, and ultrafilter Membrane filtration, drying under reduced pressure, that is.

[0038] (2) Preparation of ethanol extract of Piper longum

[0039] Take longicorns, dry, crush, sieve, soak in 7-10 times ethanol for 12 hours, filter to get the clarified solution, continue to soak the residue for 12 hours, combine the two filtrates, centrifuge at 3000rpm for 15 minutes, separate the supernatant, evaporate to dryness in a water bath and concentrate , and then dried under reduced pressure into a dry extract, crushed, and passed through a 100-mesh sieve.

[0040] (3) Preparation of clove ethano...

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Abstract

The invention relates to a natural pharmaceutical composition and a preparation method thereof. The natural pharmaceutical composition comprises the following components: a fructus piperis longi and syzygium aromaticum water-decocted concentrated extract, a fructus piperis longi ethanol extract, a syzygium aromaticum ethanol extract and eugenol at the ratio of (1-3):(3-6):(3-7):(5-8). The composition has extremely good curative effect on cancer chemotherapy associated diarrhea and also has synergistic effect on cancer chemotherapy.

Description

technical field [0001] The present invention relates to a natural medicine composition, more specifically to a natural medicine composition composed of concentrated extract of longan longan clove decoction, ethanol extract of longan longan, ethanol extract of clove and eugenol, the natural medicine composition The preparation method of the medicine and the application of the natural medicine composition in the preparation of medicines for reducing cancer chemotherapy-related diarrhea and synergizing cancer treatment. Background technique [0002] Malignant tumor is one of the main diseases that endanger human survival and health at present. Its treatment methods include surgery, chemotherapy, radiotherapy, and traditional Chinese medicine treatment, and the effect of chemotherapy on tumors is particularly prominent. Chemotherapy drugs used alone or in combination can cause toxic and side effects such as diarrhea in patients. Diarrhea after tumor chemotherapy is also called...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/67A61P35/00A61P1/12A61K31/085
Inventor 石强
Owner 石强
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