Method for preparing colon-cleansing particles used before labor induction at later stage of pregnancy

Abstract

The invention discloses a method for preparing colon-cleansing particles used before labor induction at the later stage of pregnancy and aims to solve the problem of colon cleansing before labor induction at the later stage of pregnancy. The colon-cleansing particles are characterized by being prepared by the following active pharmaceutical ingredients, by weight ratio, horseweed herb, fructus cinnamomi, red clover, Chinese starjasmine stem, big alpine swertia, four-leaf ginseng, fructus psoraleae, tangerine peel, sunflower flowers, turbo cornutus solander, loranthus parasiticus and magnesium sulfate. The method includes (1), extracting volatile oil from fructus psoraleae, fructus cinnamomi and big alpine swertia coarse powder for standby use; (2), smashing turbo cornutus solander, loranthus parasiticus into fine powder for standby use; (3), adding water in horseweed herb, red clover, Chinese starjasmine stem, four-leaf ginseng, sunflower flowers and tangerine peel for decoction twice, filtering, merging filtrate, concentrating the filtrate, adding ethanol for deposition, taking superlate, recycling ethanol and concentrating to obtain thick paste; (4), adding the volatile oil obtained in step 1, the fine powder obtained in step 2 and magnesium sulfate in the thick paste obtained in step 3, uniformly stirring, forming particles, drying and obtaining the colon-cleansing particles. Clinical experiments show that the colon-cleansing particles has good colon-cleansing effect when used before labor induction at the later stage of pregnancy and are worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of medicines, in particular to a method for preparing intestinal-clearing granules used before induction of labor in late pregnancy. Background technique [0002] After the 28th week of pregnancy, due to maternal factors or fetal reasons, the method of artificially initiating uterine contraction to terminate pregnancy is called late pregnancy induction. Bowel preparation before induction of labor in late pregnancy includes stimulating intestinal peristalsis, softening and clearing feces, eliminating intestinal gas, and preventing patients from increasing the chance of contamination due to anal sphincter relaxation after anesthesia that cannot control defecation; at the same time, reducing intestinal gas filling and the presence of feces affect the operation. Clinical practice has proved that oral cleansing of the mixed water decoction of rhubarb, Glauber's salt, and licorice can also reduce abdominal distension and d...

AI Technical Summary

Problems solved by technology

This intestinal preparation method has the following defects: ①Mannitol is a hypertonic dehydrating agent, which strongly stimulates the intestinal tract and has a significant impact on the operator’s mood and sleep state; ②The last enema time of the traditional method is 6 am in the morning of the operation Entering the operating room at 8 am, during which there is not enough time for the intestinal tract to be completely emptied, and it is easy to cause pollution during the operation; ③It does not have a beneficial effect on postoperative recovery

[0003] At present, it is also reported that traditional Chinese medicine preparations are used for preoperative bowel cleansing, such as oral administration of the above-mentioned rhubarb, mirabilite, and licorice mixed water decoction. The patient's mood and sleep state are significantly affected, and laxatives such as Boziren are not easy to control the time of laxative

Therefore, there is currently a lack of a drug that is suitable for preoperative bowel cleansing, effective catharsis and does not affect sleep, and can have a beneficial effect on postoperative recovery.