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Pharmaceutical preparation for treating viral pneumonia or viral cold, and preparation method and application thereof

A technology for viral colds and viral pneumonia, which is applied in the directions of antiviral agents, pharmaceutical formulations, and medical preparations containing active ingredients to achieve the effects of convenient use, excellent application prospects and low prices

Inactive Publication Date: 2013-12-04
张真
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, for avian influenza disease, only passive treatment can be achieved, that is, anti-influenza virus drugs such as Tamiflu, etc. are taken 48 hours after the illness

Method used

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  • Pharmaceutical preparation for treating viral pneumonia or viral cold, and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example 1

[0029] (1) Add 3 mg of α-chymotrypsin to 20 ml of normal saline, and stir evenly;

[0030] (2) Slowly add 60,000 units of gentamicin to the solution obtained in step (1) to dissolve it completely.

[0031] (3) Add 3 mg of dexamethasone to the solution obtained in step (2), and stir evenly to obtain the pharmaceutical preparation.

[0032] This pharmaceutical formulation was named formulation A.

preparation example 2

[0034] A pharmaceutical preparation was prepared in the same manner as in Example 1 except that the various components were used in the following amounts, which was designated as preparation B.

[0035] normal saline

preparation example 3

[0037] A pharmaceutical preparation was prepared in the same manner as in Example 1 except that the various components were used in the following amounts, which was designated as preparation C.

[0038] normal saline

60ml

α-chymotrypsin

7mg

Gentamicin

100,000 units

Dexamethasone

7 mg.

[0039] Pharmacological Experiments in the Treatment of Viral Pneumonia Caused by H5N1 Avian Influenza Virus

[0040] sample:

[0041] White mice: LACA mice obtained from Qingdao University School of Medicine.

[0042] Avian influenza virus: genotype E H5N1 virus obtained from Qingdao University School of Medicine.

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Abstract

The invention relates to a pharmaceutical preparation for treating and / or preventing viral pneumonia or a viral cold caused by avian influenza, and a preparation method and the application thereof. With the unexpected combination of conventional drugs, the pharmaceutical preparation has an excellent effect on treating and / or preventing the avian influenza, particularly avian influenza patients, can effectively prevent and treat the viral pneumonia caused by avian influenza viruses, prevents the cross infection and the transmission of the avian influenza among humans, and has good effects on disease prevention and treatment.

Description

technical field [0001] The present invention relates to a therapeutic pharmaceutical preparation, in particular to a pharmaceutical preparation for the prevention and / or treatment of human avian influenza, especially viral pneumonia or viral influenza, and its preparation method and use, which belong to the prevention and treatment of avian influenza diseases. therapeutic area. Background technique [0002] Avian influenza, the full name of which is "avian influenza", is an animal infectious disease caused by different types of avian influenza viruses, but usually only infects birds and rarely infects pigs. [0003] Unlike many diseases, avian influenza virus infection is highly targeted and specific, usually only for a specific species, that is, birds, but as the virus mutates, the virus also crosses the species barrier and infects humans. Pathogenic avian influenza infection to humans can lead to a 60% chance of death. The case of human infection with avian influenza vir...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/48A61P31/16A61P31/12A61K31/573A61K31/7036
Inventor 张真韩淑红韩淑燕
Owner 张真
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