Rectal gelata of traditional Chinese medicine composition and preparation method thereof

A technology of rectal gel and composition, which is applied in the field of medicine, can solve the problems of affecting drug compliance and hurting the spleen and stomach of children, and achieves the effects of strong industrial practicability, scientific and reasonable inspection methods, and reduced types of use

Inactive Publication Date: 2013-12-18
苏州玉森新药开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, Chaihuang Granules, Chaihuang Tablets, soft capsules, oral liquids and other preparations have been developed and marketed, but they are all oral preparations, which are acceptable for adults, but for children, factors such as taste will affect the drug compliance, and children are "immature" Yin Zhi

Method used

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  • Rectal gelata of traditional Chinese medicine composition and preparation method thereof
  • Rectal gelata of traditional Chinese medicine composition and preparation method thereof
  • Rectal gelata of traditional Chinese medicine composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0024]

[0025] Take 150g of glycerin to moisten 60g of carbomer first, then add 1000g of distilled water, stir until swelling to obtain a gel matrix, and set aside; take 1.5g of ethylparaben and add 5ml of ethanol to dissolve it, and add it to the gel matrix; Add 420g of Bupleurum extract and 360g of Scutellaria baicalensis extract into the gel matrix, and mix well; then add 250g of triethanolamine, mix well; add distilled water to 3000g, mix well, let it stand to form 3000g of gel, and pack it into finished products.

Embodiment 2

[0027]

[0028] Take 150g of glycerin to moisten 60g of carbomer first, then add 1000g of distilled water, stir until swelling, and obtain a gel matrix for later use; take 3g of ethylparaben and add 5ml of ethanol to dissolve it, and add it to the gel matrix; Add 380g of Hu extract and 360g of Scutellaria baicalensis extract to the gel matrix, and mix well; then add 210g of triethanolamine, mix well; add distilled water to 3000g, mix well, let it stand to form 3000g of gel, and pack it into finished products.

Embodiment 3

[0030]

[0031] Take 150g of glycerin to moisten 60g of carbomer first, then add 1000g of distilled water, stir until swelling, and obtain a gel matrix for later use; take 1.8g of ethylparaben and add 5ml of ethanol to dissolve it, and add it to the gel matrix; Add 450g of Bupleurum extract and 360g of Scutellaria baicalensis extract into the gel matrix, and mix well; then add 315g of triethanolamine, mix well; add distilled water to 3000g, mix well, let it stand still, form 3000g of gel, and pack into finished products.

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PUM

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a rectal gelata of a traditional Chinese medicine composition, and also relates to a preparation method of the rectal gelata. The rectal gelata of the traditional Chinese medicine composition uses a bupleurum extract and a scutellaria baicalensis extract as active components, and uses a gel matrix, a thickening agent and a preservative as accessories, wherein the mass ratio of the active components to the accessories is (1.6-2.0):1, and preferably is (1.6-1.8):1. The preparation method of the rectal gelata is as follows: taking glycerol to wet carbomer first, then adding distilled water, stirring to swell to get the gel matrix for standby application; adding the preservative; taking the bupleurum extract and the scutellaria baicalensis extract to add into the gel matrix, and mixing evenly; then adding triethanolamine, and mixing evenly; then adding the distilled water, mixing evenly, standing to form gel, and packing into a finished product.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine composition rectal gel, and also relates to a preparation method of the rectal gel. Background technique [0002] "Upper respiratory tract infection", commonly known as "cold", or "upper flu" for short, is one of the most common respiratory diseases. According to the survey, about 70% of the population suffers from at least one cold every year, and the incidence rate is higher in autumn and winter. Pediatric colds account for about 80% of pediatric outpatient clinics. Symptomological surveys show that children's colds are characterized by runny nose, cough, nasal congestion, sneezing, and pharyngeal discomfort, and fever is more common, with an incidence rate of 25.7%. The incidence of febrile cold in children is about 0.8 times per person per year, and 10.2% of them are complicated by otitis media, pneumonia, etc., seriously affecting ...

Claims

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Application Information

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IPC IPC(8): A61K36/539A61K9/00A61K47/32A61P11/00A61P29/00A61P31/04
Inventor 玄振玉邹珊珊华琰
Owner 苏州玉森新药开发有限公司
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