Printing device for three-dimensional biological structure and printing method

Abstract

The invention discloses a printing device for a three-dimensional biological structure. The printing device comprises an execution unit with a liquid supply system, and a control unit, wherein the liquid supply system comprises an air compressor, an air capacitor communicated with an air outlet of the air compressor, and a liquid storage tank; a liquid outlet of the liquid storage tank is communicated with a liquid inlet of a spray head; a liquid inlet of the liquid storage tank is communicated with an air outlet of the air capacitor; a pressure reducing valve is arranged on a pipeline between the liquid storage tank and the air capacitor; the opening degree of the pressure reducing valve can be adjusted, and thus liquid drops at a spray nozzle of the spray head are enabled to not drop off; the height of the liquid storage tank can be adjusted, and thus the lowest end of a liquid level at the spray nozzle of the spray head is leveled with the spray nozzle of the spray head. The printing device disclosed by the invention can be widely applied to forming of biological scaffolds with various shapes, can be used for printing vascular structures and has the advantages of high printing precision, simpleness in operation, low cost and the like. Due to the adoption of the design of a replaceable clamp, a replaceable working face and a replaceable Z-shaped mounting plate, the printing device can be used for printing biological structures with different sizes and different tissue materials.

Description

Technical field [0001] The present invention relates to the technical fields of biomedical engineering and tissue engineering, in particular to a three-dimensional biological structure printing device and method. Background technique [0002] With the development of society, various traffic accidents and natural disasters have caused damage to human organs or congenital organ damage, leading to threats to many people’s lives. The traditional repair method is autologous tissue transplantation, although this method can be satisfactory. It is effective, but it sacrifices their own healthy tissues, so many people are waiting in the hospital for donor organs. However, due to the extremely limited source of donor organs, the number of people who need organs far exceeds the number of donor organs, and many patients have not waited for the donation. The body organs have died. [0003] Therefore, the extreme shortage of donor organs for organ transplantation has become a major problem face...

AI Technical Summary

Problems solved by technology

Researchers have proposed many solutions to solve the shortage of donor organs, but none of them have achieved the expected results. Until the 1980s, scientists first proposed tissue engineering technology. Its essence is to combine living cells with the matrix in a certain way. Combining materials or scaffolds to create new tissues, tissue engineering and regenerative medicine are expected to completely solve the problem of donor organ shortage, repair or replace damaged organs

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