Medicine composition for treating migraine as well as preparation method and application thereof

The technology of a composition and a medicine is applied to the pharmaceutical composition for treating migraine and the fields of its preparation and use, which can solve the problem of high cost of medication and achieve the effects of good therapeutic effect, good sedation and good effect.

Inactive Publication Date: 2013-12-25
CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are many existing prescriptions with many medicinal flavors, and the cost of medication is relatively high, which brings economic burden to patients with chronic diseases.

Method used

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  • Medicine composition for treating migraine as well as preparation method and application thereof
  • Medicine composition for treating migraine as well as preparation method and application thereof
  • Medicine composition for treating migraine as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] The preparation method of embodiment 1 pharmaceutical composition of the present invention

[0022] Prescription: Yuanhu 10g, Angelica dahurica 10g, Chuanxiong 10g.

[0023] Preparation:

[0024] (1) Weigh the raw material medicine according to the weight ratio;

[0025] (2) Take 8 times the amount of Yuanhu, reflux extraction with 60% ethanol for 3 hours, once, filter, and obtain medicinal residue 1 and medicinal liquid A;

[0026] (3) Take raw materials Angelica dahurica, Ligusticum chuanxiong and dregs 1, 8 times the amount of 60% ethanol reflux extraction 2 times, 1h each time, filter to obtain liquid B;

[0027] (4) Take medicinal solutions A and B, combine them, concentrate under reduced pressure, and dry to obtain extract powder;

[0028] (5) Take the extract powder, add appropriate amount of starch, granulate with 60% ethanol, dry, put into capsules, and get ready.

Embodiment 2

[0029] Embodiment 2 The preparation method of pharmaceutical composition of the present invention

[0030] Prescription: Yuanhu 10g, Angelica dahurica 10g, Chuanxiong 10g.

[0031] Preparation:

[0032] (1) Weigh the raw material medicine according to the weight ratio;

[0033] (2) Take the raw materials Yuanhu, Angelica dahurica, and Chuanxiong, reflux extraction with 10 times the amount of 60% ethanol twice, 1 hour each time, filter, combine the alcohol extracts, concentrate under reduced pressure, and dry to obtain the extract powder;

[0034] (3) Take the extract powder, add appropriate amount of dextrin to granulate, and dry to obtain.

Embodiment 3

[0035] Embodiment 3 The preparation method of pharmaceutical composition of the present invention

[0036] Prescription: Yuanhu 3g, Angelica dahurica 10g, Chuanxiong 10g.

[0037] Preparation:

[0038] (1) Weigh the raw material medicine according to the weight ratio;

[0039] (2) Take the raw materials Yuanhu, Angelica dahurica, and Chuanxiong, extract 8 times the amount of 60% ethanol under reflux twice, 1 hour each time, filter, combine the alcohol extracts, concentrate under reduced pressure, and dry to obtain the extract powder;

[0040] (3) Take the extract powder, add appropriate amount of dextrin to granulate, and dry to obtain.

[0041] Embodiment 3 The preparation method of pharmaceutical composition of the present invention

[0042] Prescription: Yuanhu 10g, Angelica dahurica 3g, Chuanxiong 3g.

[0043] Preparation:

[0044] (1) Weigh the raw material medicine according to the weight ratio;

[0045] (2) Take the raw materials Yuanhu, Angelica dahurica, and Chu...

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PUM

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Abstract

The invention provides a medicine composition. The medicine composition is a preparation which is prepared from the following medicinal raw materials in parts by weight: 3-10 parts of rhizoma corydalis, 3-10 parts of radix angelica dahurica and 3-10 parts of ligusticum wallichii. The invention also provides a preparation method and application of the medicine composition. The medicine composition provided by the invention has good effects of promoting blood circulation, removing stasis, stopping pain and calming mind; the 5-hydroxytryptamine level, the norepinephrine level, the dopamine level and / or the microcirculation can be effectively improved; and the medicine composition has good treatment effect on migraine and provides a new choice for the clinical medication.

Description

technical field [0001] The invention relates to a pharmaceutical composition for treating migraine, a preparation method and application thereof. Background technique [0002] Migraine is a recurring one-sided or bilateral fluctuating severe headache. It is a kind of periodic attack disease with a tendency of familial disease. Lost common primary headache. The incidence rate is 12.9%-17.6% in foreign countries and 0.985% in China, and the ratio of male to female is 1:4. Most of the patients have onset in childhood or adolescence and reach the peak in middle age. Nearly half of the patients have family history. Migraine can cause great harm to patients, so it is a hot spot in medical research to take effective measures to actively treat migraine. [0003] At present, the method for the treatment of migraine mainly contains Chinese medicine therapy and Western medicine therapy. The pathogenesis of migraine has not been fully understood, and scholars from various countries h...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/66A61P25/06A61P25/20
Inventor 彭成刘建林韩辉军郭力彭腾谢晓芳潘媛周勤梅万峰
Owner CHENGDU UNIV OF TRADITIONAL CHINESE MEDICINE
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