Oil-in-water compound cedar oil nano emulsion composition

A technology of cedar oil and nanoemulsion, which is applied in the field of medicine, can solve the problems of poor absorption effect and low bioavailability, and achieve the effects of improved storage stability, enhanced antibacterial effect, and large antibacterial range

Inactive Publication Date: 2014-01-15
NORTHWEST A & F UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the immiscibility of water and oil, and the traditional unilateral essent

Method used

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  • Oil-in-water compound cedar oil nano emulsion composition

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0059] Mix cedar oil 0.01g, bergamot essential oil 2.7g, sage essential oil 1.9g, myrrh essential oil 0.4g, clove essential oil 0.4g and stir well; add Tween-80 30.0g to the mixture and mix again, stir well , then slowly add 64.59g of distilled water dropwise to the mixture, and stir while adding. During the process of adding water and stirring, the mixture system will change from thin to viscous, and finally from viscous to thin, until it forms oil-in-water type nanoemulsion.

Embodiment 2

[0061] Composed of cedar oil 0.1g, bergamot essential oil 1.9g, sage essential oil 1.3g, myrrh essential oil 0.6g, clove essential oil 0.6g, Tween-80 35.0g, distilled water 60.5g.

Embodiment 3

[0063] Composed of cedar oil 1.0g, bergamot essential oil 1.0g, sage essential oil 2.7g, myrrh essential oil 0.9g, clove essential oil 1.0g, Tween-80 36.0g, distilled water 57.4g.

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Abstract

The invention discloses an oil-in-water compound cedar oil nano emulsion composition. The particle size of the nano medicine is 1-100nm. The composition is prepared from the following raw materials in percentage by mass: 0.01-5.4% of cedar oil, 0.01-2.7% of bergamot essential oil, 0.01-2.7% of Salvia japonica essential oil, 0.01-1.4% of myrrh essential oil, 0.01-1.3% of cloven essential oil, 30.0-45.0% of surfactant and the balance of distilled water, totaling 100%. The nano emulsion composition has obvious anti-inflammation action, can kill mold, and has excellent curative effects on bronchitis, cough, phlegm and the like.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a new dosage form of antifungal and anti-inflammatory drugs, in particular to a compound cedar oil, bergamot essential oil, sage essential oil, myrrh essential oil and clove oil nanoemulsion composition. [0002] Background technique [0003] Cedarwood essential oil, Latin scientific name Juniperus, aromatic smell, woody, but relatively dry, cedar oil appearance: light green to yellow-brown transparent liquid. The main curative effect is antibacterial, anti-inflammatory and fungicidal, and it has a significant effect on bronchitis, cough and phlegm. [0004] Bergamot essential oil, extracted from the peel of bergamot, has an emerald green appearance and a fresh taste, similar to orange and lemon, with a slightly floral aroma. It has obvious antibacterial effect and is a good urethral bacteriostatic agent and also an excellent intestinal bacteriostatic agent. [0005] Sage essential oil,...

Claims

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Application Information

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IPC IPC(8): A61K36/752A61K9/107A61P31/10A61P31/04A61P11/00A61P11/14A61P11/10
Inventor 欧阳五庆兰莹杨婷
Owner NORTHWEST A & F UNIV
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