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Compound radix pulsatillae granule and preparation method thereof

A Pulsatilla and granule technology, which can be applied in the directions of pharmaceutical formulations, medical preparations containing active ingredients, and bulk delivery, etc., can solve the problems of increasing the burden of patients suffering from medical staff and inconvenient use of Pulsatilla decoction.

Inactive Publication Date: 2014-02-05
QINGDAO AGRI UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] But common Pulsatilla decoction decoction appears to be inconvenient to use in clinical application, and medicine is easily absorbed and decomposed before reaching colon after oral administration of Pulsatillae decoction, and rectal (enema or suppository) administration also can't reach colon, and increases patient's misery and medical service Disadvantages such as the burden of personnel

Method used

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Examples

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preparation example Construction

[0006] The steps of the preparation method of the compound pulsatilla granules in the present invention are as follows:

[0007] 1. According to the formula ratio, weight 4 parts of Pulsatilla, 2 parts of Phellodendron chinense, 3 parts of Coptis and 4 parts of Qinpi Weigh the above 4 medicinal materials and crush them into small pieces;

[0008] 2. Add 10 times the amount of water for reflux extraction 3 times each time, 2h / time;

[0009] 3. The extract is concentrated and dried, added with auxiliary materials, crushed and granulated.

[0010] The present invention will be further explained below in conjunction with specific examples.

Embodiment 1

[0012] Weigh the four medicinal materials of Pulsatilla, Coptis, Phellodendron chinense, Phellodendron chinense, etc., in proportions by weight of the formula, crush them into small pieces, mix and extract 3 times, add 10 times of water each time (parts by weight, the same below), reflux and extract for 2 hours, filter, Combine the filtrate and set aside.

[0013] The extract is concentrated and concentrated to a relative density of 1.10. The concentrated solution is dried and crushed. Add appropriate amount of starch, mix, and make granular products.

Embodiment 2

[0015] Weigh the four medicinal materials of Pulsatilla, Coptis, Phellodendron chinense, Phellodendron chinense, etc. in the formula weight parts, crush them into small pieces, mix and extract 3 times, add water 10 times, reflux for extraction for 2.0 hours, filter, and combine the filtrate to stand for later use.

[0016] The extract is concentrated and concentrated to a relative density of 1.15. The concentrated solution is dried and crushed. Add appropriate amount of dextrin, mix, and make granular products.

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PUM

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Abstract

The invention belongs to the technical field of veterinary medicine and discloses a compound radix pulsatillae granule and a preparation method thereof. The preparation method is characterized by comprising the following steps: crushing four medicinal material components including radix pulsatillae, coptis, cortex phellodendri and the bark of ash, carrying out reflux extracting on the medicinal materials, concentrating the medicinal materials to a liquid extract, drying the liquid extract, mixing the liquid extract with additives, and finally preparing the mixture into granules. The extraction process of the medicine is improved on the basis of boiling decoction extraction of traditional decoction, thereby having the advantages of reducing the dose, improving the quality, and the like.

Description

technical field [0001] The invention belongs to the field of veterinary antidiarrheal preparations, and relates to a pulsatilla granule and a preparation method thereof. Background technique [0002] Piglet pullorum is an intestinal infectious disease characterized by diarrhea of ​​milky white fishy feces in suckling piglets. The disease is mainly caused by pathogenic Escherichia coli, and the pathogen is infected through the digestive tract. It is a common and frequently-occurring disease of piglets, and pullorum of piglets has occurred in almost all pig farms. The disease can occur throughout the year, but it is more common in early spring, severe winter and hot summer. It is one of several major diseases that plague breeders. [0003] The prescription of compound Pulsatilla granules is derived from Pulsatilla Decoction in Treatise on Febrile Diseases. It is composed of four herbs: Pulsatillae, Coptidis, Cortex Phellodendri and Qinpi. It has the effects of clearing heat...

Claims

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Application Information

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IPC IPC(8): A61K36/756A61K9/16A61P1/12A61P31/04
Inventor 不公告发明人
Owner QINGDAO AGRI UNIV
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