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Brain volumetric measuring system

A volume measurement, brain technology, applied in the field of brain volume measurement systems

Inactive Publication Date: 2014-02-12
FARMAR LICENSING
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Problems solved by technology

However, no studies have used optical contrast for the measurement of volumetric structural changes in brain atrophy

Method used

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Embodiment Construction

[0039]Recently, due to the advantages of non-invasiveness, cheap price, non-ionizing radiation, long-term monitoring, no space restriction and easy operation, near-infrared diffusion spectroscopy has gradually become an important measurement technology. Therefore, in view of the problems encountered in the prior art, the present invention provides a method to measure the degree of brain atrophy by using the near-infrared light diffusion spectrum imaging technology to change the volume structure of the brain atrophy and then affect the characteristics of light distribution in the brain. Carry out imaging and quantitative analysis. However, due to the high scattering characteristics of biological tissue for near-infrared light, the energy of light will be severely attenuated with the distance traveled by light in biological tissue, and this effect will naturally seriously affect the ability of light to travel in tissue. depth. However, even if the near-infrared light can only r...

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Abstract

The present invention discloses a brain volumetric measuring system which performs imaging and quantitative analysis by measuring the light distribution pattern of the light signal in brain affected by the structural differences of the brain when the light passes through the head. The brain volumetric measuring system at least comprises an optical device and an assessment device. The optical device further includes at least one optical probe and a plurality of detectors for emitting and receiving light to get a first optical signal, and the assessment device processes the first optical signal to get a second optical signal, thereby measuring the brain volume of a subject. By using the brain volumetric measuring system, the doctor could real-time diagnose the patient on outpatient treatment. Besides, the system provides a long-term data monitoring for home-care patients helping doctors to perform long-term tracking and diagnosis, and long-term evaluation of the patient's treatment.

Description

technical field [0001] The invention relates to a brain volume measurement system, in particular to a brain volume measurement system which uses near-infrared light diffusion spectrum imaging technology to analyze and observe brain volume structural changes. Background technique [0002] Brain atrophy is an irreversible brain lesion that mainly affects human cognition and memory functions, such as: mild cognitive impairment, Alzheimer's disease, multiple sclerosis, schizophrenia , alcoholism and dementia. The pathological mechanism of brain atrophy mainly involves progressive biochemical and structural changes in the brain, which initially occur at the cellular and synaptic stages, and eventually lead to neuronal death resulting in the loss of nerve cells and the gray and white matter of the brain tissue atrophy. Moreover, the loss of these nerves and synapses in the cortical and subcortical regions of the brain will lead to severe atrophy of the affected areas, including:...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61B5/107A61B5/1455
CPCA61B2576/026G06T2207/10088G06T7/0012G06T2207/20076A61B5/4064G06T2207/30016A61B5/055A61B2562/046A61B5/1075G06T2200/04A61B5/0073G16H30/40
Inventor 孙家伟庄竞程谢曜声
Owner FARMAR LICENSING
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