Forage additive for preventing egg-laying hen fatty liver syndrome and application thereof

A technology for fatty liver syndrome and feed additives, which is applied in the field of feed production in animal husbandry and can solve the problem of low bacterial synthesis

Inactive Publication Date: 2014-02-26
FEED RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the scientific community generally believes that although there are different types and quantities of bacteria in the intestines of an

Method used

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  • Forage additive for preventing egg-laying hen fatty liver syndrome and application thereof
  • Forage additive for preventing egg-laying hen fatty liver syndrome and application thereof
  • Forage additive for preventing egg-laying hen fatty liver syndrome and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] ——Contain the preparation of the laying hen feed of additive of the present invention

[0031]Pyrroloquinoline quinone disodium salt (gifted by Shanghai Medical Life Science Research Center, produced by chemical synthesis, purity 99.9%) was mixed with starch diluent in a dark environment to make 0.01% diluent. When preparing feed for laying hens, add an appropriate amount of pyrroloquinoline quinone disodium salt diluent (to ensure that the final content of pyrroloquinoline quinone disodium salt in laying hen feed is 0.08 mg / kg to 0.16 mg / kg) first added to In the premixed feed, it is then mixed with other feed ingredients. For example, the target dosage of pyrroloquinoline quinone disodium salt in compound feed is 0.08 mg / kg, and 800 g of 0.01% diluent needs to be added per ton of compound feed.

[0032] The prepared layer feed containing pyrroloquinoline quinone disodium salt is packaged in a light-proof woven bag lined with (black) plastic film, stored in a cool and...

Embodiment 2

[0034] ——Contain the preparation of the laying hen feed of additive of the present invention

[0035] Pyrroloquinoline quinone disodium salt (gifted by Shanghai Medical Life Science Research Center, produced by chemical synthesis, purity 99.9%) was mixed with starch diluent in a dark environment to make 0.8% diluent. When preparing feed for laying hens, add an appropriate amount of pyrroloquinoline quinone disodium salt diluent (to ensure that the final content of pyrroloquinoline quinone disodium salt in laying hen feed is 0.08 mg / kg to 0.16 mg / kg) first added to In the premixed feed, it is then mixed with other feed ingredients. For example, the target dosage of pyrroloquinoline quinone disodium salt in compound feed is 0.08mg / kg, and 10g of 0.8% diluent needs to be added per ton of compound feed.

Embodiment 3

[0037] The PQQ used in the present invention may be natural or non-natural. The preferred PQQ can be pyrroloquinoline quinone and / or its pharmaceutically acceptable salt and / or ester prepared by artificial synthesis or microbial fermentation as the active ingredient.

[0038] Diluents are pharmaceutically acceptable carriers.

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PUM

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Abstract

The invention relates to a forage additive for preventing egg-laying hen fatty liver syndrome and application thereof. The forage additive is characterized in that: (1) a safe effective amount of pyrroloquinoline quinone and/or pharmaceutically acceptable salts or esters thereof are/is added into an egg-laying hen forage as the active component; (2) a lucifugal woven bag with a lined (black) plastic membrane is employed for packaging the forage when the forage is stored; and (3) the feeding time is four weeks or more. The application of the forage additive comprises that the forage additive helps fatty-liver egg-laying hens induced by high-energy low-protein daily ration to improve egg laying rate, reduce material-egg ratio, improve egg quality, inhibit vacuolar degeneration and ballooning degeneration of hepatocyte in liver tissue, reduce the content of triglycerides and total cholesterol in blood and reduce the activity of glutamic-pyruvic transaminase and glutamic oxalacetic transaminase. Therefore, pyrroloquinoline quinine has good application prospect for preventing the form and the development of egg-laying hen fatty liver syndrome, and has economic benefit.

Description

technical field [0001] The invention relates to a feed additive for preventing fatty liver syndrome of laying hens and an application thereof, belonging to the field of feed production in animal husbandry. Background technique [0002] Layer fatty liver syndrome (FLS) is a common nutritional and metabolic disease in laying hens that causes fatty degeneration of the liver due to nutritional metabolism disorders, endocrine disorders, and fat metabolism disorders. It is mainly caused by the excessive accumulation of fat in the liver cells, which affects the normal function of the liver, and even causes the rupture of liver cells in severe cases, eventually leading to intrahepatic hemorrhage and death. The liver is the core organ of substance metabolism and an important organ of the body after the brain and heart. A healthy liver is the prerequisite for maintaining normal metabolism and health of the body. Ensuring liver health is especially critical for laying hens. Because h...

Claims

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Application Information

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IPC IPC(8): A23K1/18A23K1/16
Inventor 武书庚齐广海赵芹张海军岳洪源王晶
Owner FEED RESEARCH INSTITUTE CHINESE ACADEMY OF AGRICULTURAL SCIENCES
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