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Compound microorganism active additive and applications thereof

A technology of active additives and compound microorganisms, applied in applications, animal feeds, drug combinations, etc., to achieve obvious antagonism, slow down liver damage, and overcome dust pollution.

Active Publication Date: 2014-04-16
RECOM QINGDAO BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] In order to solve the problem of drug residues and serious damage to the liver in the additives for livestock and poultry in the prior art, the present invention provides a combination of microorganisms and fermented traditional Chinese medicine, which can Composite microbial activity additive for reducing liver damage caused by drug residues

Method used

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  • Compound microorganism active additive and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] A kind of composite microbial active additive is characterized in that it is obtained through the following steps:

[0031] (1) Weigh 12kg of hawthorn, 18kg of angelica, 12kg of schisandra, 6kg of astragalus, 6kg of medlar, 13kg of capillary, 14kg of bamboo leaves, and 7kg of raw land, crush them to 60 mesh, sterilize, and add 100 The seed liquid of 100 million lactic acid bacteria, after mixing, put it in a sterile greenhouse at 37 ° C for 48-72 hours to obtain the intermediate fermentation product;

[0032] (2) Combine the fermentation intermediate with Bacillus licheniformis 10 12 CFU, Bacillus subtilis 10 12 CFU, brewer's yeast 10 14 Mix CFU, 1g of malic acid, and 10g of citric acid, add carrier and mix well.

[0033] Every 1 kg of additive is mixed with 500 kg of feed.

[0034] Mixed drink, every 1kg of additive mixed with 1000kg of water is used.

Embodiment 2

[0036] A kind of composite microbial active additive is characterized in that it is obtained through the following steps:

[0037] (1) Weigh 12kg of hawthorn, 16kg of angelica, 12kg of schisandra, 6kg of astragalus, 6kg of medlar, 16kg of capillary, 13kg of bamboo leaves, and 7kg of raw land, crush them to 60 mesh, sterilize, and add 100 The seed liquid of 100 million lactic acid bacteria, after mixing, put it in a sterile greenhouse at 37 ° C for 48-72 hours to obtain the intermediate fermentation product;

[0038] (2) Combine the fermentation intermediate with Bacillus licheniformis 10 12 CFU, Bacillus subtilis 10 12 CFU, brewer's yeast 10 14 Mix CFU, malic acid 10g, citric acid 1g, add carrier and mix well.

[0039] In this embodiment, the carrier used may be medical stone, and the weight ratio of the added amount to the fermented traditional Chinese medicine is 40:60.

[0040] Every 1 kg of additive is mixed with 500 kg of feed.

[0041] Mixed drink, every 1kg of addi...

Embodiment 3

[0043] A kind of composite microbial active additive is characterized in that it is obtained through the following steps:

[0044] (1) Weigh 11kg of hawthorn, 16kg of angelica, 14kg of schisandra, 7kg of astragalus, 7kg of medlar, 12kg of capillary, 15kg of bamboo leaves, and 10kg of raw land, crush them to 60 mesh, sterilize, and add 100 The seed liquid of 100 million lactic acid bacteria, after mixing, put it in a sterile greenhouse at 37 ° C for 48-72 hours to obtain the intermediate fermentation product;

[0045] (2) Combine the fermentation intermediate with Bacillus licheniformis 10 12 CFU, Bacillus subtilis 10 12 CFU, brewer's yeast 10 14 Mix CFU, 4g of malic acid and 6g of citric acid, add carrier and mix well.

[0046] Every 1 kg of additive is mixed with 500 kg of feed.

[0047] Mixed drink, every 1kg of additive mixed with 1000kg of water is used.

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Abstract

The invention relates to the technical field of traditional Chinese medicines for livestock and poultry, and particularly relates to a compound microorganism active additive. The compound microorganism active additive is prepared by the following steps of weighing hawthorn, angelica sinensis, fructus schisandrae, radix astragali, fructus lycii, herba artemisiae, herba lophatheri and radix rehmanniae, crushing the weighted materials to achieve 60 meshes, sterilizing, adding lactic acid bacteria in proportion, and fermenting after mixing so as to obtain an intermediate fermentation product; and uniformly mixing the intermediate fermentation product with bacillus licheniformis, bacillus subtilis, saccharomyces cerevisiae, malic acid and citric acid, adding a carrier, and uniformly mixing so as to obtain the final fermentation product. Due to the combination of the stomach-invigorating effects of microorganisms, fermented traditional Chinese medicines and acidulants, the damage on the liver caused by poisonous substances is effectively slowed, the emission of poisonous substances is promoted, and the detoxification function of the liver is improved; bacillus licheniformis and bacillus subtilis form spores, and can be used with antibiotics; the additive can increase the effective use of efficient substances and protect the internal organs from being damaged, and also can accelerate the emission of metabolic poisonous substances and reduce the residue problem of poisonous substances, thereby making due contributions to promote the development of the green breeding industry in China.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine and microorganisms for livestock and poultry, in particular to a compound microbial active additive, and also relates to the application of the compound microbial active additive. Background technique [0002] With the intensive and large-scale development of my country's breeding industry, the incidence of livestock and poultry diseases is increasing year by year, and new diseases are increasing. question. So far, there are nearly ten dosage forms of drugs (such as macrolide antibiotics and fluoroquinolones) for controlling livestock and poultry diseases on the market, but most of them are antibiotics produced by chemical synthesis or fermentation. Due to the long-term and large-scale application of these drugs , easy to produce drug resistance and drug residues, cause irreversible damage to the liver of animals, and lose part of the detoxification function, seriously affec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23K1/00A23K1/14A61K36/899A61P1/16A61K35/74A61K35/744
Inventor 赵新华骆延波刘凤彩刘玉庆齐静胡明李璐璐颜世敢
Owner RECOM QINGDAO BIOTECH CO LTD
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