Compound levamisole hydrochloride injection and preparation method thereof

Abstract

The invention relates to a compound levamisole hydrochloride injection. Every 100 parts by weight of injection contains components in parts by weight: 3-5 parts of levamisole hydrochloride, 4-6 parts of astragalus polysaccharide, 15-20 parts of ethanol, 20-30 parts of propylene glycol, and the balance of water for injection. A preparation method of the compound levamisole hydrochloride injection comprises the following steps: (1) taking a proper amount of water for injection, sequentially adding the levamisole hydrochloride and the astragalus polysaccharide, adding the other substance after one substance is dissolved completely, and stirring to dissolve completely; and (2) sequentially adding the ethanol and the propylene glycol with prescription dosage into the solution obtained in step 1, mixing evenly, adjusting the pH value of the mixed liquor, adding the water for injection into the solution to the prescription dosage, mixing, filtering, sub-packaging, potting and sterilizing at 115-126 DEG C for 25-35 minutes. Due to the combination of traditional Chinese and western medicines, and the joint action of the levamisole hydrochloride and the astragalus polysaccharide, the compound levamisole hydrochloride injection provided by the invention can effectively improve the livestock and poultry immunity, reduce the morbidity, reduce drug residues and improve the quality of livestock and poultry products, and has a special effect on low immunity of livestock and poultry caused by the parasitic disease.

Description

technical field [0001] The invention relates to the field of veterinary medicine and provides a compound levamisole hydrochloride injection and a preparation method thereof. Background technique [0002] Immunosuppressive disease is a common disease in farms. It often causes growth retardation of livestock and poultry, failure of vaccine immunity, concurrent or secondary infection of various diseases, resulting in the death or elimination of a large number of livestock and poultry, resulting in huge economic losses. In particular, cattle, sheep, pigs, chickens and other livestock and poultry are susceptible to parasite infection, resulting in poor growth, low feed utilization, and reduced resistance, resulting in reduced economic benefits for breeding enterprises. [0003] Levamisole hydrochloride is a broad-spectrum, high-efficiency, low-toxic anthelmintic commonly used in veterinary clinics and animal production. Studies have found that in addition to its deworming fu...

AI Technical Summary

Problems solved by technology

[0002] Immunosuppressive diseases are common diseases in farms, which often cause growth retardation of livestock and poultry, failure of vaccine immunity, concurrent or secondary infection of various diseases, resulting in the death or elimination of a large number of livestock and poultry, resulting in huge economic losses

Especially cattle, sheep, pigs, chickens and other livestock and poultry are susceptible to parasite infection, resulting in poor growth, low feed utilization, and reduced resistance, resulting in reduced economic benefits for breeding enterprises