Medical irrigating fluid

A rinsing solution and a pharmaceutical technology, applied in the field of medicine, can solve the problems of undisclosed mechanism of action, unclear mechanism of side effects, limited effect of preventing postoperative infection, etc.

Inactive Publication Date: 2014-09-24
济南环肽医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, further experiments found that although the flushing solution has a good effect on preventing postoperative adhesions, its effect on preventing postoperative infection is limited, and it is easily absorbed by the body, which in turn leads to various side effects
Although Chinese Patent Publication No. CN103271939 A discloses the composition and use of the flushing solution, it does not disclose its mechanism of action, and the mechanism of its side effects is still unclear

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0032] Example 1 Preparation of medical flushing solution containing 1,4,5,6-tetrahydro-2-methyl-5-hydroxyl-4-pyrimidinecarboxylic acid

[0033] The formula is as follows:

[0034] 1,4,5,6-tetrahydro-2-methyl-5-hydroxy-4-pyrimidinecarboxylic acid 0.2g

[0035] Water for injection 99.8g

[0036] The preparation method is as follows:

[0037] Weigh the prescription amount of 1,4,5,6-tetrahydro-2-methyl-5-hydroxy-4-pyrimidine carboxylic acid, add the prescription amount to water for injection, stir to dissolve, and sterilize to obtain 1,4,5 , Medical flushing solution of 6-tetrahydro-2-methyl-5-hydroxy-4-pyrimidinecarboxylic acid.

Embodiment 2

[0038] Example 2 Preparation of medical flushing solution containing 1,4,5,6-tetrahydro-2-methyl-5-hydroxyl-4-pyrimidinecarboxylic acid

[0039] The formula is as follows:

[0040] 1,4,5,6-tetrahydro-2-methyl-5-hydroxy-4-pyrimidinecarboxylic acid 0.7g

[0041] Water for injection 99.3g

[0042] The preparation method is as follows:

[0043] Weigh the prescription amount of 1,4,5,6-tetrahydro-2-methyl-5-hydroxy-4-pyrimidine carboxylic acid, add the prescription amount to water for injection, stir to dissolve, and sterilize to obtain 1,4,5 , Medical flushing solution of 6-tetrahydro-2-methyl-5-hydroxy-4-pyrimidinecarboxylic acid.

Embodiment 3

[0044] Example 3 Preparation of medical flushing solution containing 1,4,5,6-tetrahydro-2-methyl-5-hydroxyl-4-pyrimidinecarboxylic acid

[0045] The formula is as follows:

[0046] 1,4,5,6-tetrahydro-2-methyl-5-hydroxy-4-pyrimidinecarboxylic acid 1g

[0047] Water for injection 99g

[0048] The preparation method is as follows:

[0049] Weigh the prescription amount of 1,4,5,6-tetrahydro-2-methyl-5-hydroxy-4-pyrimidine carboxylic acid, add the prescription amount to water for injection, stir to dissolve, and sterilize to obtain 1,4,5 , Medical flushing solution of 6-tetrahydro-2-methyl-5-hydroxy-4-pyrimidinecarboxylic acid.

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PUM

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Abstract

The invention discloses a medical irrigating fluid, which comprises 1,4,5,6-tetrahydryl-2-methyl-4-pyrimidine carboxylic acid or 1,4,5,6-tetrahydryl-2-methyl-5-hydroxyl-4-pyrimidine carboxylic acid and water for injection, in addition, the medical irrigating fluid can contain medically acceptable preservative and / or pH regulator. According to the medical irrigating fluid, people perform a series of animal experiments, the research shows that the medical irrigating fluid has an excellent irrigation effect and safety, and plays a good role in preventing postoperation tissue adhesion and infection.

Description

technical field [0001] The invention relates to the field of medicine, in particular to a medical washing liquid. Background technique [0002] Irrigating Solution is a liquid used to clean human cavity, mucous membrane and other tissues and organs, such as Intraocular Irrigating Solution, Nasal Irrigation, Surgical Irrigation Fluids , has been widely used clinically. Medical irrigating solution is usually used to remove microorganisms and residual tissues in the human mucosa or cavity by rinsing or lavage, gently expand the mucosal space, remove residual blood and cut tissues from the surgical area, improve the environment of the surgical area, and enhance the clarity of the surgical area Degree, reduce postoperative tissue adhesion, reduce postoperative bleeding, etc. At present, many irrigants have been developed clinically, such as ophthalmic irrigants, nasal cavity irrigants, vaginal irrigants, minimally invasive surgery irrigants, electrocution surgery irrigants, and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/505A61P43/00A61P41/00
Inventor 厉保秋厉凌子高继友
Owner 济南环肽医药科技有限公司
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