Ultrasonic mechanical damage and thermal coagulation device and method based on double-frequency con-focal ultrasonic time-sharing excitation

A technology of thermal coagulation and high-frequency ultrasound, which is applied in ultrasound therapy and treatment, can solve the problems of increased risk and complication rate, tissue damage, long treatment time, etc., and achieve high-efficiency mechanical damage and thermal coagulation, and improve efficiency. Effect

Active Publication Date: 2014-12-24
XI AN JIAOTONG UNIV
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Problems solved by technology

However, HIFU still has certain limitations. The main point is that the thermal ablation or mechanical lesion produced by a single HIFU irradiation is small in size, and it takes a long time to ablate or destroy a larger tumor. It takes several hours, and it is difficult for the patient to remain still for such a long treatment time, which increases the risk and the incidence of complications
[0003] To address the above

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  • Ultrasonic mechanical damage and thermal coagulation device and method based on double-frequency con-focal ultrasonic time-sharing excitation
  • Ultrasonic mechanical damage and thermal coagulation device and method based on double-frequency con-focal ultrasonic time-sharing excitation
  • Ultrasonic mechanical damage and thermal coagulation device and method based on double-frequency con-focal ultrasonic time-sharing excitation

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[0027] The present invention will be described in detail below in conjunction with the accompanying drawings and embodiments.

[0028] Based on the application status of high-intensity focused ultrasound, the present invention proposes a method based on dual-frequency confocal power ultrasonic time-sharing excitation to finally improve the efficiency of ultrasonic mechanical damage and thermal coagulation. On the one hand, the absorption of ultrasound by biological tissue increases linearly with its frequency, and the higher the frequency, the more energy will be converted into tissue temperature rise, so high-frequency ultrasound is more suitable for thermal ablation of tissue; the other On the one hand, the threshold of cavitation in tissue or liquid is proportional to the frequency of ultrasound, that is, the lower the frequency, the lower the cavitation threshold, so low-frequency ultrasound is more likely to produce ultrasonic cavitation, which is more suitable for mechani...

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Abstract

The invention provides an ultrasonic mechanical damage and thermal coagulation device and method based on double-frequency con-focal ultrasonic time-sharing excitation. High-low-frequency ultrasonic waves or low-high-frequency ultrasonic waves are sequentially transmitted by controlling a double-array-element annular con-focal power ultrasonic transducer in a time-sharing working mode or the ultrasonic transducer and phase-change micro-nano liquid drops are combined in use to achieve the purpose of improving ultrasonic mediated visco-elastic medium mechanical damage and thermal coagulation efficiency.

Description

technical field [0001] The invention relates to ultrasonic physics and ultrasonic instruments and applications thereof, in particular to an efficient ultrasonic mechanical damage and thermal coagulation device and method based on dual-frequency confocal ultrasonic time-sharing excitation. Background technique [0002] High-intensity focused ultrasound (HIFU), as a non-invasive ultrasound treatment technology, mainly utilizes the good tissue penetration and directionality of ultrasound to gather and form a high-intensity sound field in body tissues, through the transient high-temperature effect of ultrasound, The cavitation effect and mechanical effect destroy the target tissue in the focal region, but there is no damage to the tissue on the acoustic path and the surrounding tissue, so that the purpose of non-invasive treatment or surgical resection of the lesion can be achieved. According to its mechanism of action, HIFU damages the target tissue in two main ways: thermal ef...

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Application Information

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IPC IPC(8): A61N7/02
Inventor 万明习徐姗姗刘晓东宗瑜瑾陆明珠
Owner XI AN JIAOTONG UNIV
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