The invention discloses a magnetic refrigeration cooling device and control system which comprises a magnetic refrigeration system, a cooling system and a driving control system. The magnetic refrigeration system comprises a magnetic field system, a magnetic working medium device, a refrigeration end and a heating end, a magnetic working medium is placed into the magnetic field system, the magnetic torque of the magnetic working medium is neat or disordered along with change of a magnetic field direction, the cooling system comprises a pump, a disk seamless cooling pipeline, a disk seamless heat absorption pipeline, a draft tube and cooling liquid, and the cooling liquid circulates in the pipeline in a reciprocating manner under driving of the pump. By the aid of a single-chip microcomputer in the adaptive on-off driving control system for an intelligent temperature control switch, on one hand, periodic change of the magnetic field system is controlled, on the other hand, the pump is controlled to drive the cooling liquid to periodically and circularly flow, the cooling efficiency of the system is higher than that of a traditional single cooling system by the aid of magnetic refrigeration technology, magnetic leakage can be effectively decreased, a cooled part can be intelligently cooled, energy is saved, environments are protected, pollution is avoided, and noise is quite low.