Method for preparing skin cleaning liquid containing tanshinone

A technology of skin cleaning and tanshinone, which is applied in the field of traditional Chinese medicine preparations, can solve the problems of not being easy to carry and apply, and achieve the effects of improving curative effect, increasing effective substances, and high content of effective substances

Active Publication Date: 2015-01-21
JIANGSU QILIKANG SKIN PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] Aiming at the problems of the existing medicines for external use on the skin that are not easy to carry

Method used

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  • Method for preparing skin cleaning liquid containing tanshinone

Examples

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Comparison scheme
Effect test

Embodiment 1

[0028] A preparation method of a skin cleansing solution containing tanshinone, comprising the steps of:

[0029] The 1st step, get tanshinone powder 1Kg, trimethoprim 1Kg, vitamin A 2Kg, vitamin E 2Kg, mix uniformly, obtain mixture I;

[0030] Step 2, take another 30Kg of chitosan, 1Kg of glycerol monostearate, 20Kg of glycerin, 20Kg of propylene glycol, 4Kg of acetic acid, 0.5Kg of emulsifier, 0.5Kg of preservative, and 70Kg of water, mix evenly after heating, and the heating temperature is 60 °C, mixture II was obtained;

[0031] Step 3, mix mixture I and mixture II evenly;

[0032] The preparation method of said tanshinone powder is as follows: take Danshen root and pulverize it, add 90% ethanol to heat and reflux to extract once, the weight of ethanol is twice the weight of Danshen, filter, combine the filtrates, recover ethanol under reduced pressure and concentrate it into a thick paste, Wash with hot water, the temperature of the hot water is 80°C, dry at 80°C, grind...

Embodiment 2

[0036] A preparation method of a skin cleansing solution containing tanshinone, comprising the steps of:

[0037] The 1st step, get tanshinone powder 3Kg, trimethoprim 3Kg, vitamin A 4Kg, vitamin E 4Kg, mix uniformly, obtain mixture I;

[0038] Step 2, take another 40Kg of chitosan, 3Kg of glycerol monostearate, 40Kg of glycerin, 40Kg of propylene glycol, 8Kg of acetic acid, 0.8Kg of emulsifier, 0.8Kg of preservative, and 100Kg of water, mix well after heating, and the heating temperature is 70 °C, mixture II was obtained;

[0039] Step 3, mix mixture I and mixture II evenly;

[0040] The preparation method of the described tanshinone powder is as follows: take Danshen root, grind it, add 90% ethanol and heat it under reflux to extract 3 times, the weight of ethanol is 4 times of the weight of Danshen, filter, combine the filtrate, recover ethanol under reduced pressure and concentrate it into a thick paste, Wash with hot water, the temperature of the hot water is 80°C, dry ...

Embodiment 3

[0044] A preparation method of a skin cleansing solution containing tanshinone, comprising the steps of:

[0045] The 1st step, get tanshinone powder 2Kg, trimethoprim 2Kg, vitamin A 3Kg, vitamin E 3Kg, mix uniformly, obtain mixture I;

[0046] Step 2, take another 35Kg of chitosan, 2Kg of glycerol monostearate, 30Kg of glycerin, 30Kg of propylene glycol, 5Kg of acetic acid, 0.6Kg of emulsifier, 0.6Kg of preservative, and 80Kg of water, mix well after heating, and the heating temperature is 65 °C, mixture II was obtained;

[0047] Step 3, mix mixture I and mixture II evenly;

[0048] The preparation method of said tanshinone powder is as follows: take Danshen root and grind it, add 90% ethanol to heat and reflux to extract twice, the weight of ethanol is 3 times of the weight of Danshen, filter, combine the filtrates, recover ethanol under reduced pressure and concentrate it into a thick paste, Wash with hot water, the temperature of the hot water is 70°C, dry at 80°C, grind...

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Abstract

The invention relates to a method for preparing skin cleaning liquid containing tanshinone, and belongs to the technical field of traditional Chinese medicine preparation. The method comprises the following steps: uniformly mixing tanshinone powder, trimethoprim, vitamin A and vitamin E to obtain a mixture I; heating chitosan, glycerol monostearate, glycerin, propylene glycol, acetic acid, an emulsifier, preservative and water, and uniformly mixing the components to obtain a mixture II; uniformly mixing the mixture I with the mixture II to obtain the skin cleaning liquid; the skin cleaning liquid containing tanshinone provided by the invention is high in content of effective substance and is convenient to use, aluminum oxide is added to remove some impurities in the tanshinone powder, to further improve the effective substance in the extractum. The chitosan and the acetic acid can well promote the transdermal absorption of salvia miltiorrhiza so as to improve the curative effect.

Description

[0001] technical field [0002] The invention relates to a preparation method of a skin cleansing liquid containing tanshinone, which belongs to the technical field of traditional Chinese medicine preparations. [0003] Background technique [0004] The total amount of human skin lipids generally accounts for 3.5% to 6.0% of the total skin weight, but the lowest can be only 0.3%, and the highest can reach 10.0%. Clinically, skin is roughly divided into several types according to the amount of fat on the skin surface: oily skin, dry skin, neutral skin, and mixed skin. It was found that the average sebum secretion rate of people with oily skin was significantly higher than that of people with dry skin, and the difference was statistically significant. For people with oily skin, the secretion function of sebaceous glands is relatively strong, the face feels greasy, difficult to clean, and has an unsightly shine; at the same time, it is also prone to some corresponding skin d...

Claims

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Application Information

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IPC IPC(8): A61K31/58A61K47/36A61K47/12A61P17/10
CPCA61K9/0014A61K31/07A61K31/355A61K31/505A61K31/58A61K36/537A61K47/12A61K47/36A61K2300/00
Inventor 吴克
Owner JIANGSU QILIKANG SKIN PHARMA
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