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Application of sika deer spleen extract in anti-fatigue medicaments

An extract, the technology of sika deer, is applied in the field of traditional Chinese medicine to achieve the effects of improving the ability to withstand hypoxia under normal pressure, prolonging swimming time, and reducing physiological load

Active Publication Date: 2015-02-04
北京中京丰创科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Deer spleen tastes bad, not for human consumption, little research

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] . Weigh 250g of sika deer spleen, remove the surface connective tissue, and cut into 0.5cm thick slices;

[0024] . Add 600ml of normal saline and grind for 5 minutes;

[0025] . Put the deer spleen suspension in a water bath and raise the temperature to 65°C, adjust the pH value to 6.0, add 5.1g of papain, 2.3g of bromelain and 2.4g of neutral protease and keep it in the water bath for 2 hours;

[0026] . Continue to add 3.5g 5'-phosphodiesterase to incubate for 2h;

[0027] . Centrifuge the suspension at 4000g for 10 minutes to get the supernatant, perform ultrafiltration with a 10KD ultrafiltration membrane to obtain an ultrafiltrate, and spray dry to obtain deer spleen extract powder with anti-fatigue effect.

Embodiment 2

[0029] . Weigh 250g of sika deer spleen, remove the surface connective tissue, and cut into 0.5cm thick slices;

[0030] . Add 750ml of normal saline and grind for 5 minutes;

[0031] . Put the deer spleen suspension in a water bath and raise the temperature to 67°C, adjust the pH value to 6.0, add 7.5g of papain, 1.9g of bromelain and 1.7g of neutral protease and keep it in the water bath for 2 hours;

[0032] . Continue to add 3.7g 5'-phosphodiesterase to incubate for 2h;

[0033] . Centrifuge the suspension at 4000g for 10 minutes to get the supernatant, perform ultrafiltration with a 10KD ultrafiltration membrane to obtain an ultrafiltrate, and spray dry to obtain deer spleen extract powder with anti-fatigue effect.

Embodiment 3

[0035] . Weigh 250g of sika deer spleen, remove the surface connective tissue, and cut into 0.5cm thick slices;

[0036] . Add 550ml of normal saline and grind for 5 minutes;

[0037] . Put the deer spleen suspension in a water bath and raise the temperature to 65°C, adjust the pH value to 6.0, add 7.3g of papain, 1.8g of bromelain and 1.8g of neutral protease and incubate in the water bath for 1 hour;

[0038] . Continue to add 3.5g 5'-phosphodiesterase to incubate for 2h;

[0039] . Centrifuge the suspension at 4000g for 10 minutes to get the supernatant, perform ultrafiltration with a 10KD ultrafiltration membrane to obtain an ultrafiltrate, and spray dry to obtain deer spleen extract powder with anti-fatigue effect.

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PUM

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Abstract

The invention relates to application of a sika deer spleen extract in anti-fatigue medicaments. Animal experiments prove that the sika deer spleen extract prepared by a process disclosed by the invention can improve the hypoxia tolerance of mice at normal pressure, improve the resistance to sodium nitrite toxicity of the mice, prolong the swimming time of the mice, reduce the content of urea nitrogen in serum of the mice after strenuous exercises, reduce the physiological load of the mice after motion, increase the glycogen reserve of the mice and realize a significant anti-fatigue effect, and can be used for preparing the medicaments and health foods with the anti-fatigue effect.

Description

Technical field: [0001] The invention relates to the application of sika deer spleen extract in anti-fatigue drugs, uses the sika deer spleen extract to prepare medicines or health products, and belongs to the technical field of traditional Chinese medicine. technical background: [0002] With the increase of social pressure and the acceleration of the pace of life, more than 35% of the world's people are in a state of fatigue. Fatigue can cause endocrine disorders and immunity decline, seriously affecting people's quality of life. In recent years, many scholars have done a lot of work on anti-fatigue. The anti-fatigue effects mainly include traditional Chinese medicine and chemical medicine. Traditional Chinese medicine mainly includes American ginseng and rhodiola rosea. , There are certain side effects of taking chemical medicine for a long time. [0003] The taste of deer spleen is not good, so it is not eaten by people, and there is little research on it. The whole ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/01A23L1/312A23L1/29A61P39/00A61K35/26A23L13/20A23L33/00
Inventor 孟庆繁王迪周毓麟彭小君逯家辉滕利荣程瑛琨谢晶卢文倩贾东旭王贞佐刘艳
Owner 北京中京丰创科技有限公司
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