Traditional Chinese medicine combination for treating bone injury and fracture and preparation method of traditional Chinese medicine combination

A composition and traditional Chinese medicine technology, applied in the directions of drug combination, pharmaceutical formulation, drug delivery, etc., can solve the problems of prolonged disease course and painful period of patients, slow effect of controlling symptoms, great pain in surgery, etc., and achieve early physiological healing period, callus Forms a rapid, high cure rate effect

Inactive Publication Date: 2015-03-25
青岛申达高新技术开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine treatment of fractures mainly includes manual reduction and external fixation, such as small splint bandage fixation and continuous traction, etc. For critically ill patients, open reduction and internal fixation are generally adopted. people don't want to accept
Traditional Chinese medicine often treats pa

Method used

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  • Traditional Chinese medicine combination for treating bone injury and fracture and preparation method of traditional Chinese medicine combination
  • Traditional Chinese medicine combination for treating bone injury and fracture and preparation method of traditional Chinese medicine combination
  • Traditional Chinese medicine combination for treating bone injury and fracture and preparation method of traditional Chinese medicine combination

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0080] The preparation method of the external ointment of the present invention includes:

[0081] First, 1500g of Panax notoginseng, 1500g of Dragon's blood, 1500g of frankincense, 1500g of myrrh, 1500g of cinnamon and 1500g of Qianghuo are vaporized into crystals by distillation, crushed for later use, and then 1500g of the above ground maple peel, 1500g of safflower, 1500g of safflower, and horse money Seed 1500g, catechu 1500g, Chuanwu 1500g, cinnamon 1500g, Tougucao 1500g, Angelica 1500g, Tripterygium 1500g, Weilingxian 1500g, Earthworm 1500g, Scorpion 1500g, add 10 times the weight of the raw materials Soak in sesame oil for 7-10 days, heat to extract the active ingredients, boil on high fire, and reduce the fire power after the sesame oil boils, until the medicine is dark brown on the outside and burnt yellow inside, remove the medicine residue, continue to smelt the medicine, and stir constantly , The smoke turns from white to green, refining to dripping into beads; fry t...

experiment example 2

[0094] Experimental example 2: Cumulative toxicity test:

[0095] The traditional Chinese medicine preparation of the present invention was taken orally to the mice at 7.69, 19.18 and 43.21g crude drugs / kg for 15 weeks (1.0ml / 100g body weight, twice a day) for 15 weeks and 3 weeks after drug withdrawal, the results showed that: the traditional Chinese medicine of the present invention The preparation had no significant effect on the hair, behavior, urine and feces, body weight, organ weight, blood picture, liver and kidney function, blood sugar, blood lipid and other indicators of rats. No abnormal changes were found in the organs by naked eyes. The results of histological examination showed that the medication 15 There were no obvious changes in the organs of the rats after weeks and 3 weeks after drug withdrawal. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention is less toxic to rats after long-term medication, and there is ...

experiment example 3

[0096] Experimental example 3: Acute transdermal toxicity test results

[0097] The externally used compound preparation of the medicine of the present invention has the effects of dispelling wind and dampness, promoting blood circulation and dredging collaterals, and is used for treating rheumatism, rheumatoid arthritis and other diseases. Based on this, an acute dermal toxicity test was first performed to observe whether the acute dermal toxicity of the drug to rats is actually non-toxic.

[0098] Test substance: the preparation ointment for external use of the present invention. Weigh 50g of the test substance and add distilled water to make a 50% paste for later use.

[0099] Experimental animals: 20 SD rats were provided by the Experimental Animal Center of Shandong Academy of Traditional Chinese Medicine, each half male and half male, weighing 180-220g, first-class animals (Yidong Zi No. 08-25), the source of feed is the same as above. Animal room environment: temperature: 22...

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PUM

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Abstract

The invention provides a traditional Chinese medicine combination for treating bone injury and fracture. The traditional Chinese medicine combination for oral administration comprises the following crude drugs: Indian bread, red sage root, cornus officinalis, acanthopanax bark, rhizome of Sichuan lovage, large leaf gentian root, loranthus muberry mistletoe, achyranthes root, safflower, ground beetle, caulis spatholobi, rhizome of drynaria, giant knotweed, psoralea fruit, elderberry, buck grass, cassia twig, earthworm, red peony root, heroubill geranium, ledebouriella root and epimedium; the traditional Chinese medicine combination for external use comprises the following raw materials: anisetree bark, myrrh, frankincense, dipsacus root, notoginseng, safflower, dragon's blood, nux vomica, black catechu, radix aconiti preparata, cassia, caulis impatientis, dahurian angelica root, triperygium wilfordii, Chinese clematis, notopterygium root, earthworm and dried body of scorpion. The traditional Chinese medicine combination has the efficacies of promoting blood circulation to remove blood stasis, promoting reunion of fractured bones, removing stasis to relieve pain and promoting focus repair, and is applicable to the treatment of various types of bone injury and fracture, and is high in cure rate. The traditional Chinese medicine combination ensures that patients are free from the pain of bone fracture and are not required to take strong paregoric. The traditional Chinese medicine combination ensures that callus is rapidly formed and the physiological healing stage is obviously advanced, thereby achieving the purpose of treating bone injury and fracture. The traditional Chinese medicine combination for oral administration has the effects of relieving distension, relieving pain, eliminating stasis, engendering the new and promoting the callus growth, and the traditional Chinese medicine combination for external use can ensure that the callus is rapidly formed and the physiological healing stage is obviously advanced.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine composition for treating bone injuries and fractures and a preparation method thereof. Background technique [0002] Fracture is a common and frequently occurring disease in clinical practice. The Department of Orthopedics and Traumatology of Traditional Chinese Medicine has a history of thousands of years in my country and has accumulated rich experience in fracture treatment. "Nei Jing" says: "Qi hurts pain, shape hurts and swells." Wang Bing's note: "Qi is invisible, so it hurts pain, and blood has shape, so it hurts and swells." Fractures damage qi and blood, causing blood vessels to run away from the meridians, stagnation of bad blood, and blood stasis, resulting in abnormal circulation of qi and blood, and stasis persists, resulting in swelling and pain. "If the blood is not invigorated, ...

Claims

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Application Information

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IPC IPC(8): A61K36/71A61K36/889A61K36/896A61P19/08
CPCA61K36/076A61K9/0014A61K9/06A61K9/2059A61K9/2068A61K35/62A61K35/646A61K36/11A61K36/126A61K36/185A61K36/21A61K36/232A61K36/236A61K36/237A61K36/238A61K36/254A61K36/258A61K36/286A61K36/296A61K36/324A61K36/328A61K36/35A61K36/37A61K36/40A61K36/47A61K36/48A61K36/486A61K36/487A61K36/51A61K36/537A61K36/54A61K36/56A61K36/57A61K36/65A61K36/704A61K36/71A61K36/714A61K36/716A61K36/889A61K36/896A61K47/10A61K47/44A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 不公告发明人
Owner 青岛申达高新技术开发有限公司
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