Chickweed Extract and Its Uses

An extract, the technology of vine vine, applied in the field of vine vine extract, can solve the problems of cumbersome operation and high energy consumption, achieve the effect of less dosage, high yield, and improvement of pain writhing reaction

Active Publication Date: 2018-01-05
NINGBO DACHANG PHARMA +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the method disclosed in this application is cumbersome to operate and has high energy consumption.

Method used

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  • Chickweed Extract and Its Uses
  • Chickweed Extract and Its Uses
  • Chickweed Extract and Its Uses

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Take 1.0kg of Yunnan medicinal materials (batch number: 131110), add 8 times the amount of 95% ethanol to reflux for extraction for 3 hours, extract 3 times, filter and combine the extracts, concentrate under reduced pressure at 60°C until there is no alcohol smell, add deionized water to 4L to make Dissolve, centrifuge, take the D101 macroporous adsorption resin on the supernatant (the ratio of the amount of medicinal material to the resin is that 1kg of medicinal material requires 300ml of D101 macroporous resin after swelling and pretreatment with absolute ethanol), the diameter-to-height ratio of the resin column is 1:8, The sample loading flow rate is 1.0BV / h. After the sample loading, the elution flow rate is 5BV / h. First, use deionized water to elute the resin column 2BV, discard the flow-through liquid and water eluent, and then wash with 85% ethanol. De-resin column 6BV, collect the eluate of 85% ethanol, concentrate under reduced pressure at 60°C, and dry to ob...

Embodiment 2

[0029] Take 1.0 kg of Yunnan medicinal materials (batch number: 131226), add 8 times the amount of 95% ethanol to reflux for extraction for 3 hours, extract 3 times, filter and combine the extracts, concentrate under reduced pressure at 60 ° C until there is no alcohol smell, add deionized water to 4 L Dissolve, centrifuge, take the D101 macroporous adsorption resin on the supernatant (the ratio of the amount of medicinal material to the resin is that 1kg of medicinal material requires 300ml of D101 macroporous resin after swelling and pretreatment with absolute ethanol), the diameter-to-height ratio of the resin column is 1:8, The sample loading flow rate is 1.0BV / h. After the sample loading, the elution flow rate is 5BV / h. First, use deionized water to elute the resin column 2BV, discard the flow-through liquid and water eluent, and then wash with 85% ethanol. De-resin column 6BV, collect the eluate of 85% ethanol, concentrate under reduced pressure at 60°C, and dry to obtain...

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Abstract

A disclosed paederia scandens extractive comprises iridoid glucosides compounds, and is characterized in that the iridoid glucosides compounds are mainly composed of 20.0%-50.0%of paederosidic acid, 2.0% -25.0% of paederoside and 1.0% -10.0% of methyl paederosidate. The paederia scandens extractive is prepared according to the following method: a), performing ethanol extraction on a paederia scandens medicinal material to obtain an extraction liquid; and b) concentrating the extraction liquid to not have alcohol smell, applying to macroporous adsorption resin for chromatography, successively using water and ethanol with the concentration of 80-90% for elution, collecting the eluate, and performing reduced-pressure drying, so as to obtain the paederia scandens extractive. The invention also provides application of the paederia scandens extractive to prepare medicines capable of reducing uric acid, also easing pain and resisting gout arthritis.

Description

technical field [0001] The present invention relates to an extract of vine vine and its use. Background technique [0002] Chicken Yateng is the above-ground part or whole plant of Rubiaceae Paederia scandens (Lour.) Merr. It is a traditional Chinese herbal medicine, also known as chicken shit rattan, cowhide jelly, Jieshu rattan, bullshit rattan, smelly rattan, breeze Rattan, etc., Cercis japonica tastes glucoside, flat in nature, enters the liver, stomach, and large intestine meridians, and has the effects of eliminating food accumulation, dispelling wind and activating blood circulation, relieving pain and reducing swelling. Distributed in many countries in China and Southeast Asia, domestic and foreign studies on the pharmacological effects and clinical application of Gallus vine mainly focus on anti-inflammatory, analgesic and treatment of digestive system diseases. In recent years, the chemical composition studies have shown that Sagittaria mainly contains sulfur-cont...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/74A61P19/06A61P19/02A61P29/00
CPCA61K31/7048A61K36/74A61K2236/333A61K2236/51A61K2236/55A61K2300/00
Inventor 吴彤沈幸光沈龙海周海凤李默影乐心逸张乐乐颜仁杰张雪张美璇王娴娴刘艺
Owner NINGBO DACHANG PHARMA
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