Perfusion solution for controlling malignant pleural effusion

Abstract

The invention discloses a perfusion solution for controlling malignant pleural effusion for solving the treatment problem of malignant pleural effusion. The perfusion solution is characterized by being prepared from the following active pharmaceutical ingredients: arisaema fargesii buchet, ramose galla chinensis, herba lycopi, mussel, halloysit, periostracum cicada, fruits of bitter bottle gourd, sweet clover, rhizoma kaempferiae, pulvis aci, mussel and ulva lactuca. Clinical experiments prove that the perfusion solution has the characteristics of good curative effect and relatively high safety in treatment of malignant pleural effusion and is worthy of clinical application and popularization.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine, in particular to a perfusate for controlling malignant pleural effusion. Background technique [0002] Malignant pleural effusion (MPE) is one of the common complications in patients with advanced tumors. Patients often have different clinical manifestations such as progressive dyspnea, cough and chest pain, which not only seriously affect the quality of life of patients, but also often lead to poor survival. shortened lifespan and increased mortality. [0003] Traditional treatment methods for malignant pleural effusion include surgical pleural stripping, intrathoracic chemotherapy, pleural adhesion drug injection, etc., but the overall treatment effect is unsatisfactory, with many complications and severe side effects. In recent years, hyperthermic pleural perfusion therapy has provided a new idea and theoretical technical support for the treatment of malignant pleural effusion. ...

AI Technical Summary

Problems solved by technology

[0004] At present, there are two main perfusion fluids for hyperthermic pleural perfusion therapy: one is normal saline, which has poor timeliness in controlling pleural effusion and has a high recurrence rate; the other is chemotherapy drugs, such as cisplatin and nedaplatin, whose mechanism of action lies in the local Anti-cancer and promotion of pleural adhesions, but clinically, due to excessive adhesion promotion, a large amount of cellulose is deposited on the pleura, capillaries and fibroblasts in the pleura grow into the cellulose, become granulation tissue, and become thicker The dense, dense capsule forms an organized pleural fibrous plate, which wraps the lung tissue extensively and hard, lacks elasticity, restricts thoracic activity, severely reduces respiratory function, and increases the recurrence of pleural effusion.

[0005] Therefore, there is still a lack of clinically effective pleural perfusion fluid that can effectively improve respiratory function and reduce the recurrence rate.