Application of a traditional Chinese medicine composition in alleviating visual fatigue and preventing, delaying and treating myopia and its complications

A composition and myopia technology, applied in the direction of drug combination, medical preparations containing active ingredients, medical raw materials derived from molluscs, etc., can solve the problems of lack of theoretical guidance and research on myopia

Active Publication Date: 2018-01-05
BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Chinese patent document CN103768283A once disclosed a kind of traditional Chinese medicine for treating various eye diseases, which included saffron in different proportions, fruit of medlar, fruit of sand garden, fruit of ligustrum lucidum, fruit of plantain, fruit of Schisandra, fruit of green scorpion, seed of cassia, honeysuckle, jasmine, It is made of 27 Chinese herbal medicines such as white chrysanthemum, stone flower, and dense Mongolian flower. In addition, Chinese patent document CN1168277A also discloses a vision granule, which is composed of raw rehmannia, rehmannia glutinosa, medlar, chrysanthemum, poria cocos, plantain seed, schisandra, It is made of 14 traditional Chinese medicinal materials such as Radix Changshen and Phellodendron Phellodendri. The traditional Chinese medicine formula provided by the above-mentioned patent documents is composed of traditional Chinese medicine ingredients such as nourishing blood and promoting blood circulation, nourishing liver and kidney, clearing liver and improving eyesight, and can be used for outer eye and inner eye on the basis of syndrome differentiation. There are many miscellaneous diseases in ophthalmology, and there is no specific theoretical guidance and research for myopia

Method used

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  • Application of a traditional Chinese medicine composition in alleviating visual fatigue and preventing, delaying and treating myopia and its complications
  • Application of a traditional Chinese medicine composition in alleviating visual fatigue and preventing, delaying and treating myopia and its complications

Examples

Experimental program
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Effect test

Embodiment 1

[0022] The crude drug formula of the traditional Chinese medicine composition of this example is as follows: Codonopsis pilosula 25g, Sophora japonicus 10g, Cork 8g, Astragalus complanatus 6g, Pearl powder 3g, Amber powder 3g and Chuan Fritillaria 6g.

[0023] The raw materials of the above formula are mixed, crushed and passed through an 80-100 mesh sieve to obtain raw raw materials powder, and the above-mentioned powder is filled into a commercially available capsule shell to form a capsule, wherein each capsule contains 0.5g of the fine powder.

Embodiment 2

[0025] The crude drug formula of the traditional Chinese medicine composition of this embodiment is as follows: Codonopsis pilosula 20g, Sophora japonicus 10g, Cork 10g, Astragalus complanatus 10g and pearl powder 1.5g.

[0026] After mixing the above-mentioned raw materials, pulverizing them, decocting them with water 20 times the weight of the medicinal materials, decocting and extracting 2 times, each extraction for 2 hours, and then collecting and combining the extracts, and the extracts are concentrated The extract with a density of 1.15 is diluted with 7 times the volume of the extract and filtered to obtain a clarified extract; the clarified extract is passed into the macropores with a flow rate of 10 times the bed volume / hour for adsorption, washing, and analysis. The adsorption resin column is first washed with water, then washed with 20% ethanol, and finally analyzed with 50% ethanol; the analyzed solution is recovered to alcohol-free, concentrated, spray-dried to obtain...

Embodiment 3

[0028] The crude drug formula of the traditional Chinese medicine composition of this embodiment is as follows: Codonopsis pilosula 25g, Sophora japonicus 10g, Cork 10g, Astragalus complanatus 10g, Pearl powder 1.5g, Amber powder 1.5g and Chuan Fritillaria 6g.

[0029] The raw materials of the above formula are mixed, after preliminary pulverization, the ultrafine powder is made into 1-10μm ultrafine powder by ultrafine pulverization technology, and the above ultrafine powder is mixed with physiological saline to form a suspension to prepare a liquid, wherein each 5ml of physiological saline Mixed with 1.0g of superfine powder.

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Abstract

The invention discloses an application of a traditional Chinese medicine composition in alleviating visual fatigue and preventing, delaying and treating myopia and its complications. Part Huaijiao, 3-15 parts by weight Phellodendron Phellodendri, 5-15 parts by weight Shayuanzi and 1-3 parts by weight pearl powder, preferably also include 1-3 parts by weight amber powder and 6-15 parts by weight Chuan Fritillaria. Among them, Dangshen and Shayuanzi benefit yang, invigorate the spleen and improve eyesight, and increase the function of retinal photoreceptor cells are the monarch drugs; Huaijiao and Cortex Phellodendri can clear the liver and improve eyesight, bitter cold and harden yin, and clear the deficiency heat of the retinal pigment cell layer are the ministerial drugs; pearl powder calms the nerves and strengthens the body , to strengthen the tenacity of scleral tissue as an adjuvant drug, the above-mentioned medicinal materials are formulated with "Yin Yang Jian Yin" as the treatment principle, the taste of the medicine is simple, the property of the medicine is mild, and they cooperate with each other and act synergistically. Inhibit the deformation of sclera, strengthen the function of retinal pigment cells, so as to prevent, delay and control the development of myopia.

Description

Technical field [0001] The invention relates to the application of a traditional Chinese medicine composition, in particular to the application of a traditional Chinese medicine composition in alleviating asthenopia and preventing, delaying and treating myopia and its complications, and belongs to the field of traditional Chinese medicine preparations. Background technique [0002] Mankind has entered the age of informatization and network. Physical activity is decreasing and the workload of mental work is increasing. The times have changed people’s lifestyles. The visual system has to receive more information (90% of external information is received through the eyes ), the eyes are the body's most sensitive organ and the most fatigued organ at present. In order to meet long-term close reading and fine manipulation, the human eye needs to adjust for long-term adaptability when working at close range, leading to myopia in the crowd The incidence of the disease is greatly increased...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/756A61P27/10A61K35/618
Inventor 马东丽
Owner BEIJING TONGREN HOSPITAL AFFILIATED TO CAPITAL MEDICAL UNIV
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