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Liver protection medicine

A drug, hepatitis B technology, applied in the field of Chinese patent medicines for liver protection drugs, can solve the problem of poor treatment effect of hepatitis B

Inactive Publication Date: 2015-08-26
GUANGXI MEDICAL UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a new composition of Chinese herbal medicine with hepatoprotective effect, so as to solve the problem of poor therapeutic effect of hepatitis B

Method used

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Experimental program
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Effect test

Embodiment Construction

[0006] 1. Preparation of Hepatitis B Granules:

[0007] 1. A prescription of liver-protecting drug Hepatitis B Granules: Ligustrum lucidum, Eclipta, Spatholobus, Bupleurum, Salvia, Chicken bone grass, Haijinsha, Prunella vulgaris, capillary, verbena 8g each, 80g in total.

[0008] 2. The hepatitis B granules (YGKL) according to claim 1, the preparation method of the granules is as follows: the optimal water extraction process of the second hepatitis granules is 10 times the amount of water, decocting 3 times, 1.5h each time. The granulation method is best with dry paste powder:starch:dextrin:sucrose=5:6:4:2.

[0009] 2. Pharmacodynamic research content:

[0010] 1. Study on the protective effects of Bgan Granules on chemical liver injury and immune liver injury in mice.

[0011] 2. Study on the anti-hepatic fibrosis effect and mechanism of Yigan Granules.

[0012] 3. Effects of Bgan Granules and its drug-containing serum on hepatic stellate cells.

[0013] The research me...

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Abstract

The invention relates to a medicine, namely hepatitis B particles, for resisting against hepatitis B viruses. The medicine comprises a plurality of Chinese herbal medicines such as glossy privet fruits, eclipta alba, caulis spatholobi, radix bupleuri, salvia miltiorrhiza, abrus cantoniensis hance, lygodium japonicum, selfheal, oriental wormwood and verbena in a compatibility mode, and a novel Chinese herbal medicine composition for effectively treating hepatitis B is developed. Through long-term researches of the inventor, the hepatitis B particles have the obvious protection effects on mice acute chemical liver injuries caused by carbon tetrachloride, acetaminophen, D-galactosamine and the like, immunological liver injuries caused by concanavalin A and rat chronic liver fibrosis. In addition, the hepatitis B particles and drug serum of the hepatitis B particles can restrain liver HSC-T6 proliferation and collagen synthesis. By means of the medicine, a new natural liver protection medicine is possibly provided for treating acute and chronic hepatitis b, the chemical liver injuries and the hepatic fibrosis.

Description

technical field [0001] The invention relates to a hepatoprotective medicine, in particular to a Chinese patent medicine of the hepatoprotective medicine prepared from Chinese herbal medicines. Background technique [0002] Liver disease refers to acute and chronic liver diseases caused by viral hepatitis, fatty liver, alcoholic liver and other causes. In addition to viral infection, liver damage caused by various liver damage factors may have the pathological characteristics of liver cell necrosis, inflammation and secondary fibrosis. Liver injury is not an independent disease name, but a pathological change, which is the common pathological basis of various liver diseases. Chemical and drug injuries are acute and chronic liver injuries caused by chemical toxic substances such as carbon tetrachloride and D-galactosamine. Hepatic fibrosis refers to the pathological process in which the proliferation and degradation of extracellular matrix such as collagen in the liver are o...

Claims

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Application Information

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IPC IPC(8): A61K36/85A61K9/16A61P31/20A61P1/16
Inventor 黄仁彬杨欣王丽惠葛文漪何开嫩林兴方芳郭雪峰陈庆全
Owner GUANGXI MEDICAL UNIVERSITY
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