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Chinese herba preparation for treating primary hypertension and application thereof

A technology of essential hypertension and traditional Chinese medicine preparations, which is applied in the direction of medical raw materials derived from Ginkgo biloba, medical preparations containing active ingredients, and drug combinations, which can solve the problems of insignificant effects and slow onset of effects, and reduce adverse effects Response, quick onset, less toxic and side effects

Inactive Publication Date: 2015-10-21
QINGDAO LANSHENGYANG PHARMA & BIOTECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Antihypertensive drugs need long-term or life-long application, drug safety and patient tolerance are very important, traditional Chinese medicine treatment of high blood pressure drugs have few side effects and stable drug effect, can be used safely for a long time, and have broad prospects, but existing prevention and treatment of high blood pressure Traditional Chinese medicines have insignificant effects, slow onset and other deficiencies. It is of great significance for the clinical treatment of essential hypertension to seek a Chinese medicine preparation with significant effects, fast onset and convenient administration.

Method used

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  • Chinese herba preparation for treating primary hypertension and application thereof
  • Chinese herba preparation for treating primary hypertension and application thereof
  • Chinese herba preparation for treating primary hypertension and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0038] The traditional Chinese medicine preparation in Example 1 of the present invention is mainly prepared from the following raw materials in parts by weight: 23 parts of Ganmutong, 26 parts of Dianchangshan, 15 parts of Gastrodia elata, 12 parts of Eucommia ulmoides, 16 parts of Chinese yam, 8 parts of Moutan bark, and 9 parts of Ginkgo biloba , 6 parts of Scutellaria baicalensis, 7 parts of Albizia juniper, 9 parts of jujube seed and 5 parts of licorice.

[0039] The preparation method is as follows:

[0040] (1) Take each medicinal material, crush it, add 8 times the total weight of the medicinal material, soak in water for 2 hours, decoct for 3 hours, filter; add the filter residue to 5 times the total weight of the medicinal material, decoct for 2 hours, and filter; combine the two filtrates, decompress Concentrate to an extract with a relative density of 1.10 at 60°C, add ethanol until the alcohol content is 70% (v / v), let it stand for 24 hours, take the supernata...

Embodiment 2

[0043] The traditional Chinese medicine preparation of Example 2 of the present invention is mainly prepared from the following raw materials in parts by weight: 30 parts of Ganmutong, 35 parts of Dianchangshan, 21 parts of Gastrodia elata, 18 parts of Eucommia ulmoides, 22 parts of Chinese yam, 12 parts of Moutan bark, and 14 parts of Ginkgo biloba , 12 parts of Scutellaria baicalensis, 13 parts of Albizia Julibrissin, 15 parts of jujube seed and 13 parts of licorice.

[0044] The preparation method is the same as in Example 1.

Embodiment 3

[0046] The traditional Chinese medicine preparation of Example 3 of the present invention is mainly prepared from the following raw materials in parts by weight: 25 parts of Ganmutong, 32 parts of Dianchangshan, 16 parts of Gastrodia elata, 15 parts of Eucommia ulmoides, 20 parts of Chinese yam, 11 parts of Moutan bark, and 12 parts of Ginkgo biloba , 9 parts of Scutellaria baicalensis, 10 parts of acacia bark, 13 parts of jujube seed and 9 parts of licorice.

[0047] The preparation method is as follows:

[0048] (1) Take each medicinal material, pulverize it, add 9 times the total weight of the medicinal material, soak in water for 3 hours, decoct for 2 hours, filter; add the filter residue to 6 times the total weight of the medicinal material, decoct for 2 hours, and filter; combine the two filtrates, decompress Concentrate to an extract with a relative density of 1.10 at 60°C, add ethanol until the alcohol content is 80% (v / v), let it stand for 24 hours, take the supernata...

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Abstract

The invention belongs to the technical field of traditional Chinese medicine and relates to a Chinese herba preparation for treating primary hypertension and the application thereof. The Chinese herba preparation is prepared with clematis filamentosa dunn, clerodendrum yunnanense, gastrodia elata, eucommia ulmoides, Chinese yam, moutan bark, folium ginkgo, scutellaria baicalensis, cortex albiziae, spina date seeds and liquorice. The Chinese herba preparation is reasonable in medicine composition, great in synergistic effect, used for treating the primary hypertension, obvious in treatment effect, stable in pharmacological effect and small in medicine side effect, and the significant clinic promotion value is achieved.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine preparation for treating essential hypertension. Background technique [0002] According to the WHO standard, the normal blood pressure of the human body is systolic blood pressure <140mmHg and (or) diastolic blood pressure <90mmHg, beyond this range can be diagnosed as hypertension. Hypertension is a common cardiovascular disease defined as a persistent increase in systemic arterial pressure. Hypertension secondary to kidney, endocrine, and nervous system diseases is called secondary hypertension, accounting for 5% to 10% of hypertensive patients; and hypertension whose cause has not been clarified so far is called primary hypertension. hypertension. Essential hypertension accounts for more than 90% of hypertensive patients, and is often accompanied by disorders of fat and glucose metabolism, as well as functional or o...

Claims

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Application Information

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IPC IPC(8): A61K36/8988A61P9/12
CPCA61K36/16A61K36/46A61K36/48A61K36/484A61K36/539A61K36/71A61K36/716A61K36/725A61K36/855A61K36/8945A61K36/8988A61K2236/331A61K2236/39A61K2236/51A61K2300/00
Inventor 刘春同
Owner QINGDAO LANSHENGYANG PHARMA & BIOTECH CO LTD
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