Medicine composition for preventing postoperative inflammatory ileus and application thereof

A composition and a technology for intestinal obstruction, applied in the field of traditional Chinese medicine, can solve problems such as prolonging hospitalization time, and achieve the effects of improving intestinal wall edema, promoting gastrointestinal motility, and promoting inflammation subsidence.

Inactive Publication Date: 2015-12-30
刘凯
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Early postoperative inflammatory bowel obstruction is a mechanical, dynamic, and coexisting syndrome caused by inflammatory exudation and edema of the intestinal wall due to trauma and anesthesia after laparotomy. 20%, which is also the more common complication after abdominal surgery, which prolongs the postoperative hospital stay and brings pain to the patient

Method used

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  • Medicine composition for preventing postoperative inflammatory ileus and application thereof

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Comparison scheme
Effect test

Embodiment 1

[0011] The preparation of embodiment 1 Chinese medicine enema

[0012] Weigh 2.5kg of Penglaicao, 2.5kg of Smilax, 0.9kg of Cyperus, 1.3kg of Qingsilong, 1.5kg of Bupleurum, 0.3kg of Daidaihua, 3.3kg of Desmodium, 0.5kg of Chicory Root, 2.0kg of Gentleman and 1.5 kg of Eupatorium kg, add water to the multi-functional extraction tank and decoct twice, add 10 times the amount of water of the medicinal materials for the first time, decoct for 2 hours, take the decoction, filter, add 8 times the amount of water of the medicinal materials for the second time, and decoct Boil for 1.5 hours, combine the two decoctions, filter, concentrate to contain 1.5g of crude drug per ml, refrigerate at 2-5°C for 24 hours, filter the refrigerated solution, add 0.1% preservative and stir well, press 100mL The specification of / bag is sub-packed, obtains Chinese medicine enema liquid.

Embodiment 2

[0013] Example 2 Study on curative effect of traditional Chinese medicine enema in treating postoperative inflammatory bowel obstruction

[0014] 62 patients with early postoperative inflammatory bowel obstruction, aged 41-73 years, average (61.8±7.2) years, 34 males, 28 females, including 7 cases of cholecystectomy, 26 cases of acute suppurative appendectomy, gastric 10 cases of duodenal perforation surgery, 1 case of ectopic pregnancy surgery, 8 cases of gastric cancer surgery, 6 cases of uterine fibroid surgery, 4 cases of cesarean section surgery. All patients met the diagnostic criteria for early postoperative inflammatory bowel obstruction. Intestinal obstruction occurred 7-18 days after abdominal surgery, confirmed by plain X-ray film and abdominal CT, accompanied by symptoms such as fever and elevated white blood cells. The patients were randomly divided into two groups, 31 cases of patients treated with conventional Western medicine were the control group, and 31 case...

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Abstract

The invention discloses a medicine composition for preventing postoperative inflammatory ileus and an application thereof. The medicine composition is prepared from the following raw materials in parts by weight: 21 to 30 parts of knotteflower phyla herb, 21 to 30 parts of chinaroot greenbrier, 6 to 11 parts of herba elsholtziae, 10 to 16 parts of lycopodium hamiltonii, 12 to 19 parts of Chinese thorowax root, 2 to 4 parts of citrus aurantium, 28 to 40 parts of lysimachia christinae hance, 3 to 6 parts of chicory root, 17 to 23 parts of quisqualis indica and 12 to 19 parts of herba lycopi. The medicine composition can promote gastrointestinal peristalsis, can stimulate the Qi of spleen and stomach and can promote the running of dross; moreover, the medicine composition can reach a disease location by retention enema, the edema of intestinal walls can be alleviated, the inflammation resolution can be promoted, and the conglutination is prevented.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine, and in particular relates to a pharmaceutical composition for preventing and treating postoperative inflammatory intestinal obstruction and its application. Background technique [0002] Early postoperative inflammatory bowel obstruction is a mechanical, dynamic, and coexisting syndrome caused by inflammatory exudation and edema of the intestinal wall due to trauma and anesthesia after laparotomy. 20%, which is also a relatively common complication after abdominal surgery, which prolongs the postoperative hospital stay and brings pain to the patient. Contents of the invention [0003] The object of the present invention is to provide a pharmaceutical composition for preventing and treating postoperative inflammatory intestinal obstruction and its application. [0004] In order to achieve the purpose of the present invention, the inventor has carried out a large number of e...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/90A61K36/896A61P1/00A61P29/00
Inventor 不公告发明人
Owner 刘凯
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