The invention relates to the technical field of functional food, in particular to a series of compositions with bowel-relaxing and toxin-expelling effects and application of the series of compositions. The series of compositions mainly comprise a composition A, a composition B, a composition C and a composition D, the composition A is mainly composed of a dark plum extract, a mulberry extract, a radish seed extract, a wolfberry extract, a hawthorn extract, a cassia seed extract, a corn stigma extract, a honeysuckle extract, a momordica grosvenori extract, a hemp seed extract, a bunge cherry seed extract, a dried orange peel extract, a jujube extract, a licorice extract and a sweetening agent; the composition B mainly comprises olive oil, a heavy metal chelating agent, a sweetening agent, fruit powder and a thickening agent; the composition is mainly prepared from plant comprehensive enzymes, water-soluble dietary fibers, fructus cannabis oligopeptide and a sweetening agent. The composition D mainly consists of lactic acid bacteria powder, pea peptide, ginseng peptide or ginseng extract, a thickening agent and a sweetening agent. The traditional Chinese medicine composition can efficiently realize intestinal regulation, bowel relaxing, bowel relaxing and toxin expelling.