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Model-estimation-based biological toxicity estimation method

A technology of biological toxicity and model prediction, applied in special data processing applications, instruments, electrical digital data processing, etc., can solve the problems of application limitations, non-inclusion, etc., and achieve the effect of reducing environmental pollution and avoiding damage

Inactive Publication Date: 2015-12-30
CHINESE RES ACAD OF ENVIRONMENTAL SCI
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Problems solved by technology

However, since the built-in data of the model are all biological toxicity data in North America, and do not include local endemic species in China, there are great limitations in application

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Embodiment Construction

[0026] The above and other technical features and advantages of the present invention will be described in more detail below in conjunction with the accompanying drawings.

[0027] Step 1, the selection of surrogatespecies:

[0028] For a certain substance, collect and sort out the existing biological toxicity data of the substance. Among all the included toxicity data, the aquatic animal toxicity data mainly includes 48 or 96h EC50 / LC50, and the toxicity end point is mainly lethal or exercise inhibition effect; The toxicity data of algae is mainly 72 or 96h EC50; the toxicity data of wildlife (mainly birds and mammals) is mainly 96h LD50. The selection criteria of the data are as follows: (1) For substances with relatively stable chemical properties, use the data obtained from the running water experiment. When there is a lack of data, the data obtained from semi-static and static experiments can also be used; (2) A control experiment must be set up in the experiment. The experim...

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Abstract

The invention relates to the field of estimation of toxic substances in environments, and specifically discloses a model-estimation-based biological toxicity estimation method, which comprises the following steps of 1, selecting a surrogate species; 2, performing toxicity estimation to obtain toxicity data of an unknown species by virtue of the surrogate species; 3, screening estimation data. The biological toxicity estimation method is applied to toxicity researches on species, and a water quality criterion deduction case research on zinc laterally proves feasibility in toxicity estimation of a species with an ICE (Interspecies Correction Estimation) model, so that the problem of incapability of accurately deducing a water quality criterion due to insufficient toxicity data of a part of pollutants is solved; damage to an experimental organism is avoided, and environmental pollution is reduced, so that a rapid, simple and environment-friendly biological toxicity research method is provided; under the condition of water quality criterion and risk assessment and the like with a requirement on a large amount of biological toxicity data for analysis, if data of a part of pollutants is insufficient, the toxicity estimation method is more economical and convenient.

Description

Technical field [0001] The invention relates to the field of prediction of toxic substances in the environment, in particular to a method for predicting biological toxicity based on model prediction. Background technique [0002] Pollutant biological toxicity data is generally obtained through experiments, but in many cases, biological toxicity data is difficult to obtain. On the one hand, it is difficult to judge the toxic effect endpoints of some pollutants, especially for some new pollutants. Therefore, toxicity experiments are difficult to carry out and it is impossible to obtain biological toxicity data; on the other hand, considering the needs of animal protection, some rare organisms It has been forbidden to carry out its toxicity experiments, such as rare and endangered organisms, so it is difficult to obtain its biological toxicity data. These scarce biological toxicity data are indispensable in the research of water quality benchmarks and risk assessment. How to carry ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G06F19/00
Inventor 冯承莲吴丰昌符志友李小峰
Owner CHINESE RES ACAD OF ENVIRONMENTAL SCI
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