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Traditional Chinese medicine composition for thyroid enlargement and preparation method thereof

A technology of goiter and traditional Chinese medicine, which is applied in the direction of drug combination, medical formula, medical raw materials derived from molluscs, etc., can solve the problems of insufficient effect and large side effects

Inactive Publication Date: 2016-02-03
QINGDAO CENT HOSPITAL
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The purpose of the present invention is to provide a traditional Chinese medicine for goiter with low treatment cost, safety, no side effects and quick effect in view of the problems that the existing drugs for treating goiter have relatively large side effects and some effects are not good enough.

Method used

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Experimental program
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Effect test

Embodiment Construction

[0072] 1. Animal simulation experiments

[0073] The results showed that the traditional Chinese medicine group could significantly reduce the levels of serum thyroglobulin antibody (TGAb) and thyroid peroxidase antibody (TPOAb) in EAT mice, improve thyroid function, and reduce or repair damaged thyroid cell structure.

[0074] 90 SPF-grade SD female rats, half male and half female, weighing 100-150 g / rat, were fed adaptively for one week, and 30 were randomly selected according to weight levels as the normal control group, and the rest were the model group. From the second week, the modeling group drank high iodine water with a concentration of 350g / L, while the control group drank distilled water. From the fourth week, the model group was subcutaneously injected with TG (TG︰CFA=1︰1) fully emulsified by complete Freund's adjuvant (CFA) into the water-in-oil form at two hind feet, twice in total, with two intervals in between. On the first day, each mouse contained 100 μg of ...

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Abstract

The invention provides a traditional Chinese medicine composition for thyroid enlargement and a preparation method thereof, and belongs to the technical field of medicine preparation. The traditional Chinese medicine composition is prepared from the following components: prunella vulgaris, dandelions, radix astragali, radix codonopsis, atractylodesmacrocephala, poriacocos, radix paeoniae alba, oysters, radix platycodi, peach seeds, radix paeoniaerubra, fritillariacirrhosa, sea floatstone, airpotatoyam rhizome, dried radix rehmanniae, rhizomacyperi, neottopteris nidus, rhodomyrtustomentosa, the root of Chinese pulsatilla, rhizomapolygonatum and cassia twigs. The components of the traditional Chinese medicine composition are subjected to medicine processing, washing and drying, and then are added with medically acceptable auxiliary materials to prepare a decoction, a tablet, a granule, powder, an injection, a capsule or a honey bolus. The medicine prepared from the medicinal materials is very good in curative effect for thyroid enlargement, and small in side effect.

Description

technical field [0001] The invention discloses a low-cost traditional Chinese medicine composition for goiter and a preparation method thereof, belonging to the technical field of medicine preparation. Background technique [0002] Radiation is the main cause of cardiovascular disease, diabetes, and cancer mutation; 2. Radiation is easy to cause damage to the human reproductive system, nervous system, and immune system; 3. Radiation is a predisposing factor for miscarriage, infertility, and teratogenic diseases in pregnant women; 4. Radiation directly affects children's development and bone marrow development, leading to vision loss, retinal detachment, and liver hematopoietic function decline; 5. Radiation can reduce sexual function, female endocrine disorders, and menstrual disorders. [0003] The thyroid gland is located about 2 to 3 cm below the "Adam's apple", and it can move up and down with it when swallowing things. The thyroid is shaped like an "H", brown-red, divi...

Claims

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Application Information

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IPC IPC(8): A61K36/8969A61P5/14A61K33/00A61K35/618
Inventor 宁建红张宁崔晓梅徐海霞
Owner QINGDAO CENT HOSPITAL
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