Traditional Chinese medicinal composition for clearing heart fire, reducing phlegm, relieving convulsion and dispelling wind, and preparation method thereof

A technology of composition and traditional Chinese medicine, which is applied in the direction of drug combination, effective ingredients of hydroxyl compounds, and pharmaceutical formulas, etc., can solve the problems of complex preparation method of Qingxin Niuhuang Tablets, difficulty in process optimization, and large dosage of patients, and achieve excellent phlegm and Hypoxia resistance, stable and controllable quality, and improved bioavailability

Inactive Publication Date: 2016-07-13
津药达仁堂集团股份有限公司乐仁堂制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The preparation method of Qingxin Niuhuang Tablets is complicated, and a large amount of raw medicinal materials are pulverized into medicine, and the dosage of patients is large, which is not conducive to quality control. Therefore, it is necessary to improve its preparation process in order to obtain a modern Chinese medicine preparation of Qingxin Niuhuang Tablets
However, many studies have found that after some traditional Chinese medicine compositions are refined by modern pharmaceutical technology, their curative effect is reduced to varying degrees compared with the original drug under the premise that the amount of crude drug remains unchanged. , containing more medicinal ingredients
The prescription of Qingxin Niuhuang Tablets is complicated and contains twenty-seven medicinal materials. There are many factors affecting the curative effect, which increases the difficulty of process optimization.

Method used

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  • Traditional Chinese medicinal composition for clearing heart fire, reducing phlegm, relieving convulsion and dispelling wind, and preparation method thereof
  • Traditional Chinese medicinal composition for clearing heart fire, reducing phlegm, relieving convulsion and dispelling wind, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1: preparation of Chinese medicine extract

[0022] 1. Prescription:

[0023] White peony 38g cinnamon 27g donkey-hide gelatin 24g platycodon 20g yam 105g Puhuang 4g soybean yellow roll 28g jujube (pitted) 45g Radix radix 22g licorice 75g white pomegranate 11g Bupleurum 20g Codonopsis 75g angelica 22g Chuanxiong 20g bitter almond 20g Fangfeng 22g Atractylodes macrocephala 37g dry Ginger 12g Scutellaria baicalensis 22g Poria cocos 24g Liushenqu 37g Bezoar 14g Realgar 12g Buffalo horn concentrated powder 16g Amber 36g Borneol 10g

[0024] Two. Preparation method:

[0025] Weigh each raw material according to the proportion of raw materials, and set aside; donkey-hide gelatin, bezoar, realgar, amber, borneol, crushed, and mixed with buffalo horn concentrated powder evenly to obtain fine powder A; cinnamon, cattail, angelica, chuanxiong, bitter almond, windproof, atractylodes , dried ginger, and Scutellaria baicalensis were extracted twice with 70% ethanol, eac...

Embodiment 2

[0026] Embodiment 2: preparation of Chinese medicine extract

[0027] 1. Prescription:

[0028]White peony 76g cinnamon 54g donkey-hide gelatin 48g platycodon 40g yam 210g Puhuang 8g soybean yellow roll 56g jujube (pitted) 90g Ophiopogon japonicus 44g licorice 150g white pomegranate 22g Bupleurum 40g Codonopsis 150g angelica 44g Chuanxiong 40g Bitter almond 40g Fangfeng 44g Atractylodes macrocephala 74g dry Ginger 24g Scutellaria baicalensis 44g Poria cocos 48g Liushenqu 74g Bezoar 28g Realgar 24g Buffalo horn concentrated powder 32g Amber 72g Borneol 20g

[0029] Two. Preparation method:

[0030] Weigh each raw material according to the proportion of raw materials, and set aside; donkey-hide gelatin, bezoar, realgar, amber, borneol, crushed, and mixed with buffalo horn concentrated powder evenly to obtain fine powder A; cinnamon, cattail, angelica, chuanxiong, bitter almond, windproof, atractylodes , dried ginger, and scutellaria baicalensis were extracted twice with 60% et...

Embodiment 3

[0031] Embodiment 3: preparation of Chinese medicine extract

[0032] 1. Prescription:

[0033] White peony 38g cinnamon 27g donkey-hide gelatin 24g platycodon 20g yam 105g Puhuang 4g soybean yellow roll 28g jujube (pitted) 45g Radix radix 22g licorice 75g white pomegranate 11g Bupleurum 20g Codonopsis 75g angelica 22g Chuanxiong 20g bitter almond 20g Fangfeng 22g Atractylodes macrocephala 37g dry Ginger 12g Scutellaria baicalensis 22g Poria cocos 24g Liushenqu 37g Bezoar 14g Realgar 12g Buffalo horn concentrated powder 16g Amber 36g Borneol 10g

[0034] Two. Preparation method:

[0035] Weigh each raw material according to the proportion of raw materials, and set aside; donkey-hide gelatin, bezoar, realgar, amber, borneol, crushed, and mixed with buffalo horn concentrated powder evenly to obtain fine powder A; cinnamon, cattail, angelica, chuanxiong, bitter almond, windproof, atractylodes , dried ginger, and Scutellaria baicalensis were extracted once with 90% ethanol, extr...

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PUM

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Abstract

The invention discloses a traditional Chinese medicinal composition for clearing heart fire, reducing phlegm, relieving convulsion and dispelling wind n, and a preparation method thereof, and belongs to the field of traditional Chinese medicine modernization. Active components of the traditional Chinese medicinal composition for clearing heart fire, reducing phlegm, relieving convulsion and dispelling wind are prepared from donkey-hide gelatin, Calculus Bovis and dry ginger. Compared with present commercial dosage forms, the composition disclosed in the invention has the advantages of stable and controllable quality, substantially improved curative effect, reduction of the taking dosage of patients, improved bioavailability, and substantial economic and social benefits.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for clearing heart-fire, resolving phlegm, calming convulsion and expelling wind and a preparation method thereof, belonging to the field of modernization of traditional Chinese medicine. Background technique [0002] Qingxin Niuhuang Tablet is a commercially available traditional Chinese medicine for clearing heart, resolving phlegm, relieving convulsions and expelling wind. It is a sugar-coated tablet, which turns brown after removing the sugar coating. , Puhuang, soybean yellow roll, jujube (pitted), Ophiopogon japonicus, licorice, white pomegranate, Bupleurum, Codonopsis, angelica, Chuanxiong, bitter almond, windproof, Atractylodes macrocephala, dried ginger, scutellaria, Poria, Liushenqu, beef , male, buffalo horn concentrate powder, amber and borneol. The preparation has the effect of clearing away heart-fire, resolving phlegm, calming convulsion and expelling wind, and is used ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P9/10A61P25/00A61P11/10A61K35/413A61K35/36A61K35/32A61K35/10A61K33/36A61K31/045
Inventor 王磊闫晓楠孙琳耿彤张宇王玉晶
Owner 津药达仁堂集团股份有限公司乐仁堂制药厂
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