Traditional Chinese medicinal composition for invigorating spleen and transforming stagnation, and preparation method thereof

A composition and technology of traditional Chinese medicine, applied in the field of traditional Chinese medicine composition for strengthening the spleen and dispelling stagnation and the field of preparation thereof, can solve the problems of increased difficulty in process optimization, unfavorable quality control, large dosage, etc., and achieve stable and controllable quality, significant economical and economical benefits. Societal benefits, effects of dose reduction for patients

Inactive Publication Date: 2016-07-13
津药达仁堂集团股份有限公司乐仁堂制药厂
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The preparation method of Jiulidan is the whole powder preparation of medicinal materials, which takes a large amount of patients and is not conducive to quality control. Therefore, it is necessary to improve its preparation process in order to obtain a modern Chinese medicine preparation of Jiulidan
However, many studies have found that after some traditional Chinese medicine compositions are refined by modern pharmaceutical technology, their curative effect is reduced to varying degrees compared with the original drug under the premise that the amount of crude drug remains unchanged. , containing more medicinal ingredients
The prescription of Jiulidan is complicated and contains eleven medicinal materials, and there are many factors that affect the curative effect, which increases the difficulty of process optimization

Method used

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  • Traditional Chinese medicinal composition for invigorating spleen and transforming stagnation, and preparation method thereof
  • Traditional Chinese medicinal composition for invigorating spleen and transforming stagnation, and preparation method thereof
  • Traditional Chinese medicinal composition for invigorating spleen and transforming stagnation, and preparation method thereof

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1: preparation of Chinese medicine extract

[0022] 1. Prescription:

[0023] Toon bark (made from vinegar) 1600g, Coptidis 80g, Magnolia officinalis (made from ginger) 160g, Brucea javanica (kernel) 10g, Citrus aurantium (stir-fried with bran) 80g, Woody fragrance 80g, Codonopsis 80g, Poria cocos 80g, Atractylodes macrocephala (stir-fried with bran) 80g , licorice 80g, angelica 160g.

[0024] Two. Preparation method:

[0025] Weigh each raw material according to the ratio of raw materials, and set aside; Magnolia officinalis (made from ginger), Citrus aurantium (stir-fried bran), woody and angelica, extract with 8 times the amount of water for 6 hours, collect volatile oil at the same time, and concentrate the extract to 50-60 Under the condition of ℃, the relative density is 1.20, and the concentrated solution A and the volatile oil B are obtained; the remaining tsubaki (vinegar), coptis and other medicinal flavors are extracted twice with 8 times the amo...

Embodiment 2

[0026] Embodiment 2: preparation of Chinese medicine extract

[0027] 1. Prescription:

[0028] Chinese toon bark (made from vinegar) 800g, Coptidis 40g, Magnolia officinalis (made from ginger) 80g, Brucea javanica (kernel) 5g, Citrus aurantium (stir-fried with bran) 40g, woody fragrance 40g, Codonopsis 40g, Poria cocos 40g, Atractylodes macrocephala (stir-fried with bran) 40g , licorice 40g, angelica 80g.

[0029] Two. Preparation method:

[0030] Weigh each raw material according to the ratio of raw materials and set aside; Magnolia officinalis (made from ginger), Citrus aurantium (stir-fried bran), woody and angelica, extract with 10 times the amount of water for 8 hours, collect volatile oil at the same time, and concentrate the extract to 50-60 Under the condition of ℃, the relative density is 1.22, and the concentrated liquid A and the volatile oil B are obtained; the remaining tsubaki bark (made from vinegar), Coptis chinensis, etc. are extracted twice with water, add...

Embodiment 3

[0031] Embodiment 3: preparation of Chinese medicine extract

[0032] 1. Prescription:

[0033] Chinese toon bark (made from vinegar) 800g, Coptidis 40g, Magnolia officinalis (made from ginger) 80g, Brucea javanica (kernel) 5g, Citrus aurantium (stir-fried with bran) 40g, woody fragrance 40g, Codonopsis 40g, Poria cocos 40g, Atractylodes macrocephala (stir-fried with bran) 40g , licorice 40g, angelica 80g.

[0034] Two. Preparation method:

[0035] The active ingredients are prepared by the following method: Weigh each raw material according to the ratio of raw materials, and set aside; Magnolia officinalis (made from ginger), Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Fructus Armeniae (fried with bran) , woody and angelica, extract with 6 times amoun...

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PUM

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Abstract

The invention discloses a traditional Chinese medicinal composition for invigorating spleen and transforming stagnation, and a preparation method thereof, and belongs to the field of traditional Chinese medicine modernization. Effective components of the traditional Chinese medicinal composition for invigorating spleen and transforming stagnation are prepared from Cortex Ailanthi and Rhizoma Atractylodis Macrocephalae. Compared with present commercial dosage forms, the composition disclosed in the invention has the advantages of stable and controllable quality, substantially improved curative effect, reduction of the taking dosage of patients, improved bioavailability, and substantial economic and social benefits.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for invigorating the spleen and dispelling stagnation and a preparation method thereof, belonging to the field of traditional Chinese medicine modernization. Background technique [0002] Jiu Lidan is a commercially available traditional Chinese medicine for invigorating the spleen and resolving stagnation. It is made from the bark of Toona sinensis, Coptis chinensis, Magnolia bark, Brucea javanica, Citrus aurantium, Woody incense, Codonopsis pilosula, Poria cocos, Atractylodes macrocephala, licorice and angelica. Jiuli Dan can invigorate the spleen and replenish qi, remove dampness and resolve stagnation. For damp-heat chronic dysentery, rest dysentery. [0003] The preparation method of Jiuli Dan is as follows: the above eleven ingredients are crushed into fine powder, sieved, mixed evenly, pilled with water, and dried. Each 500g of dry pills is coated with 90g of talcum powder and...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P1/12
Inventor 金兆祥闫晓楠孙琳耿彤张宇王玉晶
Owner 津药达仁堂集团股份有限公司乐仁堂制药厂
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