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Extracorporeal circulation pipeline of plasma exchange device with switchable blood separator

A technology for extracorporeal circulation and plasma exchange, which is applied in the field of medical devices and can solve problems such as abnormal coagulation function, insufficient injection of anticoagulant, and increased transmembrane pressure.

Active Publication Date: 2018-12-28
赵晓玲
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] The artificial liver technology relies on a smooth and stable extracorporeal blood circulation channel. A smooth circulation circuit is the prerequisite for smooth treatment. The blood flow rate of the artificial liver technology is 80~120ml / min. When the blood flow is too slow and the anticoagulant injection volume is insufficient, the patient Abnormal blood coagulation function: the value of D-dimer is higher than normal, which will easily cause the increase of transmembrane pressure (TMP), so that coagulation occurs in vitro and the clogging of the separator occurs. liver therapy interruption

Method used

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  • Extracorporeal circulation pipeline of plasma exchange device with switchable blood separator
  • Extracorporeal circulation pipeline of plasma exchange device with switchable blood separator
  • Extracorporeal circulation pipeline of plasma exchange device with switchable blood separator

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Effect test

Embodiment 1

[0025] Embodiment 1: as figure 1 , 4As shown, an extracorporeal circulation circuit of a plasma replacement device with a switchable blood separator, including a blood circulation system composed of an inlet blood vessel 1, a blood pump 2, a blood separator 3-1, and a blood return blood vessel 4, and a replacement fluid container 5. A fluid replacement system composed of a liquid inlet pipeline 6 and a liquid pump 7, a fluid drainage system composed of a fluid drainage pipeline 8, a plasma pump 9, and a waste fluid collection container 10; the blood separator includes a blood inlet 11-1, Blood outlet 11-2, plasma inlet 11-3, plasma outlet 11-4, blood inlet 11-1, blood outlet 11-2, plasma inlet 11-3, and plasma outlet 11-4 are collectively referred to as blood separator ports; After one end of the blood inlet circuit 1 is introduced into the blood vessel of the patient, the blood pump 2 is connected to the blood inlet 11-1 of the blood separator 3-1 through the other end; one ...

Embodiment 2

[0029] Embodiment 2: as figure 2 , 4 As shown, an extracorporeal circulation circuit of a plasma replacement device with a switchable blood separator, including a blood circulation system composed of an inlet blood vessel 1, a blood pump 2, a blood separator 3-1, and a blood return blood vessel 4, and a replacement fluid container 5. A fluid replacement system composed of a liquid inlet pipeline 6 and a liquid pump 7, a fluid drainage system composed of a fluid drainage pipeline 8, a plasma pump 9, and a waste fluid collection container 10; the blood separator includes a blood inlet 11-1, Blood outlet 11-2, plasma inlet 11-3, plasma outlet 11-4, blood inlet 11-1, blood outlet 11-2, plasma inlet 11-3, and plasma outlet 11-4 are collectively referred to as blood separator ports; After one end of the blood inlet circuit 1 is introduced into the blood vessel of the patient, the blood pump 2 is connected to the blood inlet 11-1 of the blood separator 3-1 through the other end; on...

Embodiment 3

[0037] Embodiment 3: as image 3 , 4 As shown, the price of the blood separator is relatively high. From the perspective of saving the cost of the patient, the present invention can also block the second blood separator 3-2 when the first blood separator 3-1 is blocked, or when the blockage is about to occur. Connected to the extracorporeal circulation pipeline of the blood purification device, since the second blood separator 3-2 and related pipelines must be pre-flushed during use, in order to solve the problem of pre-flushing of the second blood separator and related pipelines, the present invention The following solutions are proposed:

[0038] An extracorporeal circulation circuit of a plasma replacement device with a switchable blood separator, including a blood circulation system composed of an inlet blood vessel, a blood pump 2, a blood separator 3-1, and a blood return path 4, and consists of a replacement fluid container 5, an inlet liquid A fluid replacement syste...

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Abstract

The invention discloses an extracorporeal circulation pipeline of a plasma exchange device capable of switching blood separators in order to solve the problem that due to blocking of blood separators, artificial liver treatment is forced to interrupt in the artificial liver treatment technical process. The extracorporeal circulation pipeline comprises a blood circulation system, a liquid supplement system, a liquid discharge system, the standby blood separator and a pipeline body, wherein the blood circulation system is composed of a blood inlet pipeline, a blood pump, the blood separators and a blood return pipeline, the liquid supplement system comprises an exchange liquid container, a liquid inlet pipeline and a liquid pump, the liquid discharge system comprises a liquid discharge pipeline, a plasma pump and a waste liquid collection container, and the standby blood separator can be supported to cut into the extracorporeal circulation pipeline immediately through the pipeline body when the blood separators in use are blocked. Thus, the problem that due to blocking of the blood separators, artificial liver treatment is forced to interrupt in the artificial liver treatment technical process is solved.

Description

technical field [0001] The invention relates to a medical device, in particular to an extracorporeal circulation circuit of a blood purification device with a switchable blood separator. Background technique [0002] Artificial liver technology, that is, artificial liver blood purification technology, is a new medical technology that uses blood purification technology to temporarily replace liver function, so that liver cells can be restored and regenerated, and ultimately save the patient's life. From a technical point of view, it refers to plasma exchange and blood adsorption technology, that is, inflammatory substances or toxins dissolved in the blood are adsorbed to solid substances with rich surface area to remove inflammatory substances and poisons from the blood. Artificial liver technology is specially used for blood detoxification. Among them, the plasma exchange treatment mode uses the method of "exchange blood" to remove the toxins in the patient's plasma, that i...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61M1/36A61M1/34
CPCA61M1/3455A61M1/3496A61M1/3621A61M1/3633A61M1/3643A61M1/3656A61M2202/0413A61M2202/0415A61M2205/18A61M2205/3331A61M2202/0021A61M2202/0014A61M2202/0007
Inventor 赵晓玲刁玲玲胡馨予董莉刘智慧高晓露
Owner 赵晓玲
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