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Polysaccharide composition, preparation method and use thereof

A composition, technology of Codonopsis polysaccharide, applied in the field of health food

Inactive Publication Date: 2016-08-31
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If it is a patient with mild neurasthenia, eating Hericium erinaceus is a better adjuvant treatment

Method used

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  • Polysaccharide composition, preparation method and use thereof
  • Polysaccharide composition, preparation method and use thereof
  • Polysaccharide composition, preparation method and use thereof

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preparation example Construction

[0033] The object of the present invention is to provide a health food and its preparation method with the effect of preventing and improving chronic enteritis and the gastrointestinal discomfort caused by it. Whether discomfort has preventive and ameliorating effects. In order to achieve the above object, the technical scheme adopted in the present invention is to establish the rat chronic enteritis induced by TNBS (trinitrobenzene sulfonic acid) and the gastrointestinal discomfort model thereof, so as to determine and evaluate the effect of polysaccharide combination on chronic enteritis and the effect thereof. The prevention and improvement of gastrointestinal discomfort. The specific process steps are as follows:

[0034]First, 84 SPF SD rats were divided into four groups, namely blank control group, model control group, positive drug control group, Codonopsis polysaccharide group, Poria polysaccharide group, Hericium erinaceus polysaccharide group, Codonopsis polysacchar...

Embodiment 1

[0039] Example 1 Preparation of Codonopsis polysaccharide

[0040] The Codonopsis polysaccharide of the present invention is prepared by the following preparation method: After Codonopsis pilosula is crushed, water is added according to the ratio of Codonopsis pilosula: water = 0.5g: 5mL, heated and stirred at 70°C for 2 hours, and the filter residue obtained by filtering is according to the above-mentioned ratio of solid to liquid, Continue to extract twice at temperature and time, combine three extractions, concentrate under reduced pressure and centrifuge to obtain a clarified concentrate, add 7 times the volume of 95% ethanol to the clarified concentrate according to the volume ratio of clarified concentrate: 95% ethanol=1:7 After mixing, let it stand overnight at 4°C to precipitate, centrifuge to collect the precipitate, and vacuum freeze-dry to obtain Codonopsis polysaccharide.

Embodiment 2

[0041] Embodiment 2 Preparation of Poria cocos polysaccharide

[0042] The Poria cocos polysaccharide of the present invention is prepared by the following preparation method: after pulverizing Poria cocos, add water according to the ratio of Poria cocos: water = 1g: 5mL, heat and stir at 75°C for 3 hours, and filter the obtained filter residue according to the above-mentioned solid-liquid ratio and temperature Continue to extract twice with time, combine three extractions, concentrate under reduced pressure and centrifuge to obtain a clarified concentrate, add 9 times the volume of 95% ethanol to the clarified concentrate according to the volume ratio of the clarified concentrate: 95% ethanol=1:9 After mixing, let it stand overnight at 4°C to precipitate, centrifuge to collect the precipitate, and freeze-dry in a vacuum to obtain the polysaccharide.

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Abstract

The invention relates to the field of health food, in particular to a Chinese medicinal composition and a preparation method thereof, use and drugs and health food containing the Chinese medicinal composition. The invention provides a Chinese medicinal composition, which consists of Codonopsis pilosula, Poria cocos and hericium erinaceus, or is composed of Codonopsis pilosula polysaccharide, Poria cocos polysaccharide and hericium erinaceus polysaccharide. Experiments show that the Chinese medicinal composition, drugs or health food prepared by the invention are formed by scientific compatibility of medicines, can complement each other and have no toxic or side effect, have nutritional value, also can prevent and improve chronic enteritis and induced gastrointestinal discomfort, can regulate the intestinal flora, and have an auxiliary protective effect on gastric mucosa.

Description

technical field [0001] The invention relates to the field of health food, in particular to a traditional Chinese medicine composition, its preparation method, application, medicine and health food containing the traditional Chinese medicine composition. Background technique [0002] Ulcerative colitis is a common chronic intestinal disease. It is also a multi-factorial and multi-layered non-specific inflammation with unknown etiology. The main clinical manifestations are abdominal pain, diarrhea, mucus, pus and blood in the stool, etc. Epidemiological data at home and abroad show that the incidence and prevalence of ulcerative colitis are showing a clear upward trend, and it is listed by the World Health Organization as one of the modern refractory diseases . Ulcerative colitis is mostly treated with aminosalicylic acid drugs, adrenal glucocorticoids, immunosuppressants, etc., but most of the drugs have poor efficacy and have certain side effects. As a natural polymer comp...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/344A61K31/715A61P1/04A61P1/00A61P1/14A61P1/08A23L33/00A23L31/00
CPCA61K31/715A61K36/06A61K36/076A61K36/344A23V2002/00A61K2236/331A61K2236/53A61K2236/51A61K2236/39A61K2300/00A23V2200/32
Inventor 王园园胡明华马方励马忠华秦垂新陈伟鸿
Owner INFINITUS (CHINA) CO LTD
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