Traditional Chinese medicinal composition with antipyretic and anti-inflammatory effects and preparation method of traditional Chinese medicinal composition

A composition and technology of traditional Chinese medicine, applied in the field of antipyretic and anti-inflammatory traditional Chinese medicine composition and its preparation, can solve problems such as low extraction rate, influence on drug efficacy, and failure to propose active ingredients, and achieve obvious asthma effect and excellent immune-enhancing effect , good treatment and improvement effect

Inactive Publication Date: 2016-11-16
GUANGXI WUZHOU PHARMA GRP
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Since the properties of the active ingredients in the twelve medicinal materials are different, the above preparation method adopts the water extraction

Method used

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  • Traditional Chinese medicinal composition with antipyretic and anti-inflammatory effects and preparation method of traditional Chinese medicinal composition
  • Traditional Chinese medicinal composition with antipyretic and anti-inflammatory effects and preparation method of traditional Chinese medicinal composition
  • Traditional Chinese medicinal composition with antipyretic and anti-inflammatory effects and preparation method of traditional Chinese medicinal composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] (1) Weigh the following medicinal materials in parts by weight: 384 parts of mountain sesame, 384 parts of gourd tea, 384 parts of Malan grass, 384 parts of Centella asiatica, 256 parts of dog liver dish, 256 parts of fence net, 256 parts of Jade leaf golden flower, 256 parts of gall grass 256 parts of Desmodium, 256 parts of Buza Ye, 256 parts of Licorice, 572 parts of Gangmei;

[0045] (2) Get Desmodium, add 50% ethanol for extraction, the amount of ethanol is 8 times the weight of the medicinal material, heat and extract twice, each time for 2 hours, filter, and the filtrate is concentrated to a crude drug concentration of 0.5g / ml to obtain Desmodium extract The concentrated solution is adsorbed with pretreated NKA-9 macroporous resin, the ratio of diameter to height of the resin column is 1:12, the loading speed is 2BV / h, eluted with 70% ethanol, the elution speed is 2BV / h, and collected The eluent 4BV was concentrated under reduced pressure to obtain Desmodium chin...

Embodiment 2

[0052] (1) Weigh the following medicinal materials by weight: 350g mountain sesame, 350g gourd tea, 350g Malancao, 350g centella asiatica, 230g dog liver dish, 230g fence net, 230g Jade leaf golden flower, 230g gall grass, 230g desmodium, cloth residue 230g leaves, 230g licorice, 500g plums;

[0053] (2) Get Herba Desmodium, add 40% ethanol to extract, the ethanol consumption is 6 times of medical material weight part, heat extraction 3 times, extraction time is respectively 2h, 2h, 1.5h, filters, and the filtrate is concentrated to the crude drug concentration and is 0.5g / ml, desmodium extract concentrate, adsorbed with pretreated NKA-9 macroporous resin, resin column diameter-to-height ratio is 1:9, sample loading speed is 1BV / h, eluted with 50% ethanol, eluted Speed ​​3BV / h, collect eluent 5BV, eluate is concentrated under reduced pressure to obtain Desmodium chinensis concentrate;

[0054] (3) Get gourd tea, add 30% acetone to extract, the amount of acetone is 6 times of...

Embodiment 3

[0060] (1) Weigh the following medicinal materials in parts by weight: 400 parts of mountain sesame, 400 parts of gourd tea, 400 parts of Malan grass, 400 parts of Centella asiatica, 300 parts of dog liver dish, 300 parts of fence net, 300 parts of jade leaf golden flower, 300 parts, money 300 parts of grass, 300 parts of cloth dregs leaves, 300 parts of licorice, 700 parts of Gangmei;

[0061] (2) Get Desmodium, add 60% ethanol to extract, the amount of ethanol is 10 times of the weight of the medicinal material, heat and extract twice, the extraction time is 2h, 1.5h respectively, filter, and the filtrate is concentrated until the crude drug concentration is 0.5g / ml, Desmodium extract concentrate, adsorbed with pretreated NKA-9 macroporous resin, resin column diameter to height ratio is 1:15, sample loading speed is 3BV / h, eluted with 80% ethanol, elution speed is 2BV / h, collect the eluent 3BV, and concentrate the eluent under reduced pressure to obtain a desmodium concentr...

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Abstract

The invention relates to an antipyretic and anti-inflammatory traditional Chinese medicine composition, the preparation method of which mainly includes: extracting Desmodium sativa with ethanol, absorbing with NKA-9 type macroporous resin; adding acetone to gourd tea, extracting with D101 type macroporous resin; Snow grass ethanol extraction, add 3-5 times of water to the extract, and absorb with HPD-100 macroporous resin; mountain sesame, dog liver dish, fence net, jade leaf golden flower, licorice and water extraction; Malan grass, gall grass, cloth slag leaves, Add ethanol for extraction; pulverized plum into the finest powder; combine all the above extracts, add fine powder of plum and dry to obtain. Through animal efficacy experiments and clinical trials, the results prove that the traditional Chinese medicine composition provided by the invention is superior to the prior art in antipyretic, anti-inflammatory and immune-enhancing effects.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition for treating colds, in particular to an antipyretic and anti-inflammatory traditional Chinese medicine composition and a preparation method thereof. Background technique [0002] Anemopyretic cold is caused by the appearance of wind-heat evil criminals and loss of lung energy. Symptoms include severe fever, mild wind, head bloating, sweating, sore throat, cough, sticky or yellow phlegm, yellow stuffy nose, thirsty drink, red tip of tongue, thin white yellowish fur. Wind-heat cold is more common in summer and autumn, caused by exogenous wind-heat. According to traditional Chinese medicine, wind-heat cold is the superficial syndrome caused by feeling the evil of wind-heat. Syndrome: fever without sweating, or poor sweating, slight aversion to wind and cold, headache and thirst, cough and sore throat, red tip of tongue, thin white or yellow fur, floating and rapid pulse. Therapeutic Pr...

Claims

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Application Information

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IPC IPC(8): A61K36/74A61P11/00A61P29/00A61P37/04A61P11/14A61P11/06
CPCA61K36/185A61K36/19A61K36/23A61K36/28A61K36/39A61K36/48A61K36/484A61K36/515A61K36/53A61K36/74A61K2236/331A61K2236/333A61K2236/39A61K2236/55
Inventor 黄源春林艳英蔣腾川邓裕彦谭喜梅刘冠萍杨北妮
Owner GUANGXI WUZHOU PHARMA GRP
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