A traditional Chinese medicine compound preparation for treating angina pectoris of coronary heart disease and its preparation process

A technology for coronary heart disease angina pectoris and compound preparation, which is applied in the field of traditional Chinese medicine pharmacy, can solve the problems of large toxic and side effects, toxic and side effects, and high treatment costs, and achieves the effects of convenient taking and carrying, small toxic and side effects, and significant clinical medical effects.

Active Publication Date: 2019-11-01
THE AFFILIATED HOSPITAL TO CHANGCHUN UNIV OF CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The treatment of western medicine for this disease has the disadvantages of high treatment cost and large toxic and side effects; there are many medicines for treating angina pectoris in the market today, but most of them have toxic and side effects and many adverse reactions, so they are not suitable for long-term use

Method used

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  • A traditional Chinese medicine compound preparation for treating angina pectoris of coronary heart disease and its preparation process

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0101] Corydalis 5g, Rhizoma Chuanxiong 5g, Curcuma 5g, Salvia miltiorrhiza 5g, Ginseng 6g, Astragalus 5g, Woody Fragrance 3g, Panax notoginseng 6g, Borneol 0.3g, a total of nine traditional Chinese medicines, of which Corydalis Corydalis, Rhizoma Chuanxiong, Curcuma, Ginseng (Grind to 20 mesh) add 6 times the amount of 70% ethanol to reflux and extract twice, each time for 1.5 hours, filter, combine the filtrate, recover ethanol, concentrate under reduced pressure to an extract with a relative density of 1.20-1.25 (60°C) , set aside; take another 20 mesh coarse powder of notoginseng, mix it with the above extract, and dry it together (70°C), crush it into a fine powder, mix it with borneol, put it into a capsule, and get it (borneol is crushed and easy to liquefy, should be wrapped research to join).

Embodiment 2

[0103] Corydalis 10g, Rhizoma Chuanxiong 9g, Curcuma 9g, Salvia miltiorrhiza 10g, Ginseng 6g, Astragalus 10g, Muxiang 5g, Panax notoginseng 6g, and Borneol 0.3g, a total of nine traditional Chinese medicines, of which Corydalis Corydalis, Chuanxiong, Curcuma, Ginseng ( Grinding through 20 mesh) and adding 8 times the amount of 70% ethanol to reflux extraction twice, each time for 1.5 hours, filtering, combining the filtrate, recovering ethanol, and concentrating under reduced pressure to an extract with a relative density of 1.20-1.25 (60°C). Standby; take another 20 mesh coarse powder of notoginseng, mix it with the above extract, dry it together (70°C), pulverize it into a fine powder, mix it with borneol, put it into a capsule, and get it (borneol is crushed and easy to liquefy, should be grinded join in).

Embodiment 3

[0105] Corydalis 15g, Rhizoma Chuanxiong 15g, Curcuma 15g, Salvia miltiorrhiza 15g, Ginseng 15g, Astragalus 15g, Woody Fragrance 10g, Panax notoginseng 15g, Borneol 1g, a total of six traditional Chinese medicines, of which Corydalis Corydalis, Rhizoma Chuanxiong, Curcuma, Ginseng (crushed 20 meshes) plus 10 times the amount of 70% ethanol to reflux and extract twice, each time for 1.5 hours, filter, combine the filtrate, recover ethanol, concentrate under reduced pressure to an extract with a relative density of 1.20-1.25 (60°C), and set aside ; Take another 20-mesh coarse powder of Panax notoginseng, mix it with the above-mentioned extract, dry it together (70°C), pulverize it into a fine powder, mix it with borneol, put it into a capsule, and get that (borneol is crushed and easy to liquefy, and it should be grinded and added ).

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Abstract

The invention provides a traditional Chinese medicine compound preparation for treating angina pectoris and a preparation process of the compound preparation. The traditional Chinese medicine compound preparation comprises rhizoma corydalis, ligusticum wallichii, radix curcumae, salvia miltiorrhiza, ginseng, astragalus, costustoot, panax notoginseng and borneol. The compound preparation is flexible in formulating principle, clear in pharmacodynamic material and remarkable in clinical therapy effect, a formula is more faithful to traditional Chinese medicine theories, clinical practice serves as a foundation, modern scientific research serves as a basis, good therapy effects can be achieved within two months, and the capsule preparation is beneficial to drug absorption and easily carried and taken. Compared with similar medicines, the formula of the preparation is sufficient in traditional Chinese medicine theory basis, mild in medicinal property and rigorous in compatibility, clinical symptoms rapidly disappear, and excellent therapy effects can be achieved within three months.

Description

technical field [0001] The invention provides a traditional Chinese medicine compound preparation for treating coronary heart disease angina pectoris, and further discloses a preparation process of the traditional Chinese medicine compound preparation, which belongs to the technical field of traditional Chinese medicine pharmacy. Background technique [0002] In my country, coronary heart disease is the third leading cause of death after cerebrovascular disease and malignant tumors. Due to the aging of the Chinese population, the increase of serum cholesterol levels, and the increase in the prevalence of hypertension, the incidence of coronary heart disease and angina pectoris is still increasing. Therefore, it is undoubtedly of great importance to seek effective treatment methods for coronary heart disease and improve the treatment effect. social significance. The treatment of western medicine for this disease has the disadvantages of high treatment cost and high toxicity ...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/9066A61P9/10A61K31/045
CPCA61K31/045A61K36/236A61K36/258A61K36/285A61K36/481A61K36/537A61K36/66A61K36/9066A61K2236/333A61K2236/39A61K2236/51A61K2300/00
Inventor 成光宇初洪波李琳刘爱东牛春风刘艳华李庆杰娄婷婷
Owner THE AFFILIATED HOSPITAL TO CHANGCHUN UNIV OF CHINESE MEDICINE
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