Granular preparation prepared by concentrating decoction of fresh traditional Chinese medicines and preparation method of granular preparation prepared by concentrating decoction of fresh traditional Chinese medicines

A granule type and medicament technology, which is applied in the direction of medical preparations containing active ingredients, pharmaceutical formulas, plant/algae/fungus/moss components, etc., can solve the problems of low biological activity, residual processing pollution, low curative effect, etc., to achieve Improve biological activity and improve the effect of curative effect

Inactive Publication Date: 2017-01-04
北京心颐和创新国际中医药医疗技术研究院(有限合伙)
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] However, the granules prepared by the above method not only have problems such as pesticide residues of harmful substances, heavy metals exceeding the standard, or processing pollution residues, but also have low biological activity, so that their curative effect is not high.

Method used

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  • Granular preparation prepared by concentrating decoction of fresh traditional Chinese medicines and preparation method of granular preparation prepared by concentrating decoction of fresh traditional Chinese medicines
  • Granular preparation prepared by concentrating decoction of fresh traditional Chinese medicines and preparation method of granular preparation prepared by concentrating decoction of fresh traditional Chinese medicines

Examples

Experimental program
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Effect test

Embodiment 1

[0068] A variety of soups of the present embodiment are condensed into granules by low-temperature freeze-drying and condensed into five concentrated granules of astragalus and cinnamon branches, including 150 grams of fresh astragalus, 110 grams of fresh peony, 80 grams of fresh osmanthus, and 55 grams of fresh ginger. 40 grams of jujube ingredients are fresh raw materials. Add water to the raw medicinal materials of fresh products for low-temperature heating and extraction, filter, concentrate the extract into a fluid extract with a specific gravity of 1.28, dry and pulverize the dregs into a fine powder of dregs, mix the fluid extract with a specific gravity of 1.28 and the total weight of dregs 20% fine powder of medicinal dregs is stirred and mixed evenly, and then freeze-dried at low temperature to form a concentrated granule dosage form of astragalus, guizhi, and five substances with an average particle diameter of 900 μm.

[0069] The formula contains flavonoids, paeon...

Embodiment 2

[0078] Its formula and preparation method are basically the same as in Example 1, except that the first and second merged and filtered extracts are concentrated into a liquid extract with a specific gravity of 1.25, and the liquid extract with a specific gravity of 1.25 and medicinal residues 25% of the total weight of the dregs fine powder is stirred and mixed evenly.

Embodiment 3

[0080] Its formula and preparation method are basically the same as in Example 1, except that the first and second merged and filtered extracts are concentrated into a liquid extract with a specific gravity of 1.30, and the liquid extract with a specific gravity of 1.30 and medicinal residues 15% of the total weight of the dregs fine powder is stirred and mixed evenly.

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Abstract

The invention belongs to the technical field of traditional Chinese medicine and particularly relates to a granular preparation prepared by concentrating a decoction of fresh traditional Chinese medicines and a preparation method of the granular preparation prepared by concentrating the decoction of the fresh traditional Chinese medicines. The preparation method includes weighing all fresh traditional Chinese medicine materials prior to pretreatment, blending and adding water into the blended fresh traditional Chinese medicine materials for low-temperature extraction and filtration so as to obtain an extracting solution and decoction dregs; concentrating the extracting solution into liquid extract, drying the decoction dregs, grinding the dried decoction dregs into fine powder, stirring and mixing the liquid extract with the fine decoction dreg powder or part of fine decoction dreg powder uniformly, and carrying out freeze drying so as to obtain the granular preparation. The granular preparation and the preparation method thereof have the advantages that on one hand, the problem that the traditional Chinese medicine materials are prone to mildewing and deteriorating is avoided, and on the other hand, the problems of hazardous substance pesticide residues, excessive heavy metal, processing pollution residues or the like in the dried traditional Chinese medicine materials are solved; biological activity is improved, so that efficacy is enhanced.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicine preparations, and in particular relates to a kind of low-temperature freeze-drying and condensing of multiple soups with fresh herbal medicines as raw materials into granule dosage forms and a method for preparing them into granule dosage forms. Background technique [0002] my country is the birthplace of traditional Chinese medicine, with rich resources and theories of traditional Chinese medicine, and the treatment and academic level of traditional Chinese medicine are among the best in the world of traditional medicine. Thousands of years of clinical application have accumulated rich clinical experience and philosophical dialectical theory, and formed its own unique theoretical system. The overall concept and dialectical treatment are its essence, and this essence is reflected in the formation of prescriptions of. From the earliest "Fifty-two Disease Prescriptions" to the current "...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/16A61K36/9068
CPCA61K9/1682A61K36/481A61K36/54A61K36/65A61K36/71A61K36/725A61K36/9068A61K2236/331A61K2236/51A61K2300/00
Inventor 赵国林
Owner 北京心颐和创新国际中医药医疗技术研究院(有限合伙)
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