Antibody composition and application thereof for detecting immunohistochemical marker protein combination of pancreatic ductal adenocarcinoma

A technology of pancreatic ductal adenocarcinoma and antibody composition, applied in the direction of immunoglobulin, protease inhibitor immunoglobulin with anti-peptide structure, measuring device, etc., can solve the problem of lack of specific pathological diagnostic markers for pancreatic ductal adenocarcinoma There are problems such as the report of sensitive markers of lesions, so as to reduce the difficulty of interpretation, overcome the low timeliness and low specificity, and simplify the operation process
CN106290888BActive Publication Date: 2018-02-13韩晓
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Patents(China)
Current Assignee / Owner
韩晓
Publication Date
2018-02-13

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Abstract

The invention discloses an antibody composition for detecting pancreatic duct adenocarcinoma immunohistochemical marker protein compositions and application of the antibody composition. The pancreatic duct adenocarcinoma immunohistochemical marker protein compositions comprise TIMP1 and CD82. The antibody composition for detecting the protein compositions comprises monoclonal antibodies of the TIMP1 and monoclonal antibodies of the CD82. The antibody composition and the application have the advantages that the TIMP1 / CD82 compositions are used as novel pancreatic duct adenocarcinoma markers, the antibody composition can be widely used in disease identification and diagnosis and prognosis monitoring of pancreatic duct adenocarcinoma, and gaps on immunohistochemical detection in the two aspects can be filled.
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Description

technical field

[0001] The invention belongs to the field of biological detection, and relates to an antibody composition for detecting immunohistochemical marker protein combination of pancreatic ductal adenocarcinoma and application thereof. Background technique

[0002] Pancreatic cancer is the most common and serious malignant tumor in the world, known as the "king of cancer", the five-year survival rate of patients is less than 1%, and the prognosis is extremely poor. Pancreatic blood vessels and lymphatic vessels are abundant, and acini are unencapsulated, so pancreatic cancer has an insidious onset, rapid development, and is very prone to metastasis. At the same time, due to its painless growth and the absence of highly specific tumor markers, imaging techniques are still unable to detect small early-stage lesions. As a result, pancreatic cancer patients are usually diagnosed at an advanced stage. 70% of pancreatic cancers are located in the pancreatic head, pancreat...

Claims

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