Recurrent spontaneous abortion relevant microRNA and applications thereof

A technology for repeated spontaneous abortions and uses, applied in the fields of biotechnology and medicine, can solve the problems of RM identification and prediction methods that are poorly understood
CN106319031AInactive Publication Date: 2017-01-11SHANGHAI INST OF PLANNED PARENTHOOD RES +1
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SHANGHAI INST OF PLANNED PARENTHOOD RES
Publication Date
2017-01-11
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention relates to a microRNA marker for diagnosing the natural recurrent abortion, and in particular relates to a microRNA marker hsa-miR-3074 used for distinguishing the tissue suffering from natural recurrent abortion and the normal tissue. The inspection proves that the specific microRNA marker can be used for effectively diagnosing and / or predicating the natural recurrent abortion. The invention further relates to applications of the marker microRNA hsa-miR-3074 and a kit used for detecting the natural recurrent abortion.
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Description

technical field

[0001] The invention relates to the fields of biotechnology and medicine. Specifically, the present invention relates to the method and application of hsa-miR-3074-5p gene in identifying RM pathological pregnancy. Background technique

[0002] The establishment and maintenance of normal human pregnancy needs to go through a series of important steps such as embryo implantation, placenta formation, and embryonic development, which are coordinated and regulated by different systems at multiple levels. Any obstacle in any link will lead to adverse pregnancy outcomes such as spontaneous abortion. In 2005, European Society of Human Reproduction and Embryology (ESHRE, European Society of Human Reproduction and Embryology) defined "miscarriage" as: (1) a pregnancy that was positive in a urine pregnancy test or elevated in blood HCG levels, but ultrasound or histology failed to confirm pregnancy The situation is called "biochemical loss", which generally occurs befo...

Claims

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