Wound disinfecting spraying film agent and preparation method thereof

A technology for spraying film and wounds, which is applied in pharmaceutical formulations, medical preparations with non-active ingredients, and medical preparations containing active ingredients, etc. and other problems, to achieve the effect of preventing the emergence of drug-resistant bacteria, expanding the scope of the antibacterial spectrum, and preventing re-infection

Active Publication Date: 2017-02-01
GUANGDONG LUOFUSHAN SINOPHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, these pharmaceutical preparations have low bioavailability, poor sensory properties, poor moisturizing and sustained release effects, and the most important thing is that they are easy to contaminate the human body, clothes and drug

Method used

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  • Wound disinfecting spraying film agent and preparation method thereof
  • Wound disinfecting spraying film agent and preparation method thereof
  • Wound disinfecting spraying film agent and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] The wound disinfection film spraying agent described in the present embodiment comprises the following components in mass percentage:

[0021]

[0022]

[0023] The wound disinfection spray film described in this embodiment is prepared by the following steps:

[0024] (1) Add polyvinylpyrrolidone to the ethanol solution, then add p-chloro-m-xylenol, and mix to obtain solution A;

[0025] (2) dissolving chitosan hydrochloride and hypromellose in water to obtain solution B;

[0026] (3) Slowly add solution A to solution B obtained in step (2), and stir while adding to obtain solution C;

[0027] (4) Add menthol, camphor, borneol, methyl salicylate, camphor oil, peppermint oil, clove basil oil, star anise oil, turpentine, glycerin, water to the solution C obtained in step (3), to obtain the Wound disinfection spray film. .

Embodiment 2

[0029] The wound disinfection film spraying agent described in the present embodiment comprises the following components in mass percentage:

[0030]

[0031]

[0032] The wound disinfection spray film described in this embodiment is prepared by the following steps:

[0033] (1) Add polyvinylpyrrolidone to the ethanol solution, then add p-chloro-m-xylenol, and mix to obtain solution A;

[0034] (2) dissolving chitosan hydrochloride and hypromellose in water to obtain solution B;

[0035] (3) Slowly add solution A to solution B obtained in step (2), and stir while adding to obtain solution C;

[0036] (4) Add menthol, camphor, borneol, methyl salicylate, camphor oil, peppermint oil, clove basil oil, star anise oil, turpentine, glycerin, water to the solution C obtained in step (3), to obtain the Wound disinfection spray film.

Embodiment 3

[0038] The wound disinfection film spraying agent described in the present embodiment comprises the following components in mass percentage:

[0039]

[0040]

[0041] The wound disinfection spray film described in this embodiment is prepared by the following steps:

[0042] (1) Add polyvinylpyrrolidone to the ethanol solution, then add p-chloro-m-xylenol, and mix to obtain solution A;

[0043] (2) dissolving chitosan hydrochloride and hypromellose in water to obtain solution B;

[0044] (3) Slowly add solution A to solution B obtained in step (2), and stir while adding to obtain solution C;

[0045] (4) Add menthol, camphor, borneol, methyl salicylate, camphor oil, peppermint oil, clove basil oil, star anise oil, turpentine, glycerin, water to the solution C obtained in step (3), to obtain the Wound disinfection spray film.

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PUM

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Abstract

The invention discloses a wound disinfecting spraying film agent and a preparation method thereof. The wound disinfecting spraying film agent consists of the following components in percentage by mass: 0.2-0.5% of p-chloro-m-xylenol, 1.5-3.0% of menthol, 1.0-2.3% of camphor, 0.5-1.0% of borneol, 0.5-1.5% of methyl salicylate, 0.25-0.35% of camphor oil, 0.5-1.0% of peppermint oil, 0.1-0.5% of ocimi gratissimi oil, 0.1-0.5% of star anise oil, 0.1-1.0% of eucalyptus oil, 0.1-1.0% of turpentine oil, 3-6% of polyvinylpyrrolidone, 0.1-0.35% of chitosan hydrochloride, 0.1-0.3% of hydroxypropyl methylcellulose, 70-80% of ethanol, 0.5-3% of glycerol and the balance of water. The wound disinfecting spraying film agent provided by the invention has broad-spectrum bactericidal, rapid bactericidal and long-acting antibacterial functions and the like, and the wound disinfecting spraying film agent is rapid to stop bleeding and promote healing; a film can be formed on skin within several minutes so as to isolate bacteria and prevent re-infection of a wound; and in addition, the wound disinfecting spraying film agent is low in irritation of the human skin and is safe and convenient to use.

Description

technical field [0001] The invention belongs to the field of disinfectants, and in particular relates to a wound disinfection film spraying agent and a preparation method thereof. Background technique [0002] Skin is an important organ of the human body, composed of epidermis and dermis, and has important physical, chemical and biological barrier functions. It covers the surface of the whole body and has the most contact with the external environment. In daily work and life, people often suffer from skin trauma such as abrasions, cuts, scalds, and burns. Various damages caused by skin trauma, such as: increased metabolism, decreased body temperature, excessive loss of water and protein, and disorders of the endocrine and immune systems. Although most skin traumas are superficial injuries, improper treatment will lead to delayed healing, slow wound healing, and affect work and study. If not handled properly, secondary infection may leave scars and affect the appearance. T...

Claims

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Application Information

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IPC IPC(8): A61K36/57A61K9/70A61K47/36A61K47/32A61P31/04A61P17/02A61P7/04A61K31/618A61K31/125A61K31/055A61K31/045A61K31/722
CPCA61K9/7015A61K31/045A61K31/055A61K31/125A61K31/618A61K31/722A61K36/15A61K36/53A61K36/534A61K36/54A61K36/57A61K47/32A61K47/36A61K2300/00
Inventor 张清民翟锡斌谢汉凤梁银友
Owner GUANGDONG LUOFUSHAN SINOPHARM
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