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Compound plant-caused transdermal patch for treating prostatic hyperplasia and preparation method thereof

A technology of prostatic hyperplasia and transdermal patch, which is applied in the field of medicine, can solve the problems of reducing smooth muscle tension, etc., achieve the effects of eliminating inflammation and hyperplasia, improving pathological conditions, and solving drug absorption

Inactive Publication Date: 2017-02-22
FUJIAN AGRI & FORESTRY UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

α-receptor blockers can reduce smooth muscle tension, reduce lower urinary tract resistance, and improve urination status, but they can also cause toxic side effects such as hypotension, gastrointestinal reactions, and renal function damage

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] A compound plant-derived transdermal patch for the treatment of benign prostatic hyperplasia, the transdermal patch is a matrix diffusion type, and the composition of the transdermal patch includes: 10% extract mixture, 80% warm-melt pressure-sensitive adhesive, Penetration accelerator 5%, tackifier 5%;

[0030] The ingredients of the extract mixture are calculated in parts by weight: 20 parts of Pygeum africa extract, 20 parts of Saw Palmetto extract, 12 parts of pumpkin seed oil, 11 parts of Tribulus terrestris extract, 12 parts of Tongkat Ali extract, 12 parts of Cistanche deserticola extract, 12 parts of Rosa Rosa extract, 1 part of polyvinylpyrrolidone.

[0031] The warm-melt pressure-sensitive adhesive is sodium polyacrylate; the skin penetration accelerator is peppermint oil; and the tackifier is rosin resin.

[0032] A preparation method of a compound plant-derived transdermal patch for treating benign prostatic hyperplasia, the specific steps are as follows: ...

Embodiment 2

[0039] A compound plant-derived transdermal patch for treating benign prostatic hyperplasia, the transdermal patch is a matrix diffusion type, and the composition of the transdermal patch includes: 15% extract mixture, 80% warm-melt pressure-sensitive adhesive, Transdermal accelerator 2%, tackifier 3%;

[0040] The ingredients of the extract mixture are calculated in parts by weight: 20 parts of Pygeum africa extract, 20 parts of Saw Palmetto extract, 12 parts of pumpkin seed oil, 11 parts of Tribulus terrestris extract, 12 parts of Tongkat Ali extract, 12 parts of Cistanche deserticola extract, 12 parts of Rosa Rosa extract, 1 part of polyvinylpyrrolidone.

[0041] The warm-melt pressure-sensitive adhesive is sodium polyacrylate; the skin penetration accelerator is azone; and the tackifier is rosin resin.

[0042] A preparation method of a compound plant-derived transdermal patch for treating benign prostatic hyperplasia, the specific steps are as follows:

[0043] 1) Ingre...

Embodiment 3

[0049] A compound plant-derived transdermal patch for treating benign prostatic hyperplasia, the transdermal patch is a matrix diffusion type, and the composition of the transdermal patch includes: 15% extract mixture, 75% warm-melt pressure-sensitive adhesive, Transdermal accelerator 5%, tackifier 5%;

[0050] The ingredients of the extract mixture are calculated in parts by weight: 20 parts of Pygeum africa extract, 20 parts of Saw Palmetto extract, 12 parts of pumpkin seed oil, 11 parts of Tribulus terrestris extract, 12 parts of Tongkat Ali extract, 12 parts of Cistanche deserticola extract, 12 parts of Rosa Rosa extract, 1 part of polyvinylpyrrolidone.

[0051] The warm-melt pressure-sensitive adhesive is sodium polyacrylate; the skin penetration accelerator is azone; and the tackifier is rosin resin.

[0052] A preparation method of a compound plant-derived transdermal patch for treating benign prostatic hyperplasia, the specific steps are as follows:

[0053] 1) Ingre...

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PUM

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Abstract

The invention discloses a compound plant-caused transdermal patch for treating prostatic hyperplasia and a preparation method thereof. The transdermal patch comprises the main components of, by weight, 20 parts of African pygeum extract, 20 parts of serenoa serrulata extract, 12 parts of pumpkin seed oil, 11 parts of tribulus terrestris extract, 12 parts of eurycoma longifolia extract, 12 parts of boschniakia rossica extract, 12 parts of cherokee rose fruit extract and 1 part of polyvinylpyrrolidone. A preparation method includes the concrete steps of dosing, coating, covering and punching. In combination with the effects that the kidneys are invigorated, Yang is strengthened, qi is benefited, blood circulation is promoted, essence is secured, urination is reduced, and sterilization, inflammation prevention, swelling elimination, hormone regulation and tissue proliferation restraining are carried out, the transdermal patch comprehensively improves internal and external physiological states of the prostate at the physiological level of molecules, eliminates inflammation and proliferation, and recovers the prostate body; direct transdermal patching on the focus is adopted, the internal illness is treated by external treatment, in this way, medicine penetration and medicine absorption are effectively achieved for the prostate, and the pathological conditions of the prostate are directly improved for a patient.

Description

technical field [0001] The invention belongs to the field of medicine, and in particular relates to a compound plant-derived transdermal patch for treating benign prostatic hyperplasia and a preparation method thereof. Background technique [0002] Hyperplasia of prostate (BPH): benign prostatic hyperplasia (BPH) is a common and frequently-occurring disease of male elderly, and it is also a common disease in urology. The most prominent symptom in the early stage is frequent urination, especially at night. Worse, difficulty urinating in the later stage, causing serious complications: acute urinary retention, urinary tract infection, gross hematuria, bladder stones, impaired renal function, etc., which seriously affect the physical and mental health and quality of life of the elderly. According to statistics, people over 50 years old in my country The prevalence rate of men is 40%, and the prevalence rate of those over 60 years old is 50%. There are 210 million elderly people in...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/889A61K9/70A61P13/08
CPCA61K36/73A61K9/7023A61K36/185A61K36/42A61K36/64A61K36/738A61K36/889A61K47/44A61K2300/00
Inventor 魏道智宁书菊
Owner FUJIAN AGRI & FORESTRY UNIV
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