Western medicine combination for treatment of tetanus and preparation method thereof

A technology of tetanus and western medicine, applied in the field of western medicine, can solve the problems of increasing the economic pressure of patients, high treatment costs, and pain, and achieve the effect of short curative effect, low production cost and good taste

Inactive Publication Date: 2017-03-22
ZHENGZHOU ZHENGXIAN PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The disability rate of tetanus is about 10%, and the treatment of tetanus usually adopts methods such as injection antitoxin and tetanus antivenom, but these methods not only make the patient feel doubly painful in the course of treatment...

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] A western medicine combination for treating tetanus, which is composed of the following raw materials in parts by weight: 3 parts of norethindrone tablets, 0.5 parts of ox horn, 8 parts of leflunomide powder, 2 parts of silkworm cocoon shells, 2 parts of shredded tobacco, 10 parts of normal saline, 0.01 parts of vitamin C.

[0019] A preparation method of a western medicine combination for treating tetanus, the preparation method comprising:

[0020] (1) After cleaning, crushing and sterilizing the ox horns, sieve 50 meshes, mix the crushed ox horns with leflunomide powder, silkworm cocoon shells, and shredded tobacco, put them into a muffle furnace, and calcinate at 150°C for 6 minutes ;

[0021] (2) Pulverize the calcined coke-like product, then add physiological saline, vitamin C and powdered norethindrone tablets, and mix uniformly;

[0022] (3) Put the product obtained in step (2) into a rotary evaporator, and evaporate it at 85°C for 10 minutes;

[0023] (4) Th...

Embodiment 2

[0025] A western medicine combination for treating tetanus, which is composed of the following raw materials in parts by weight: 7 parts of norethindrone tablets, 2 parts of ox horn, 15 parts of leflunomide powder, 5 parts of silkworm cocoon shells, 5 parts of shredded tobacco, 50 parts of normal saline, 0.1 part of vitamin C.

[0026] A preparation method of a western medicine combination for treating tetanus, the preparation method comprising:

[0027] (1) After cleaning, crushing and sterilizing the ox horns, sieve 80 meshes, mix the crushed ox horns with leflunomide powder, silkworm cocoon shells, and shredded tobacco, put them into a muffle furnace, and calcinate at 220°C for 10 minutes ;

[0028] (2) Pulverize the calcined coke-like product, then add physiological saline, vitamin C and powdered norethindrone tablets, and mix uniformly;

[0029] (3) Put the product obtained in step (2) into a rotary evaporator, and evaporate it at 120°C for 15 minutes;

[0030] (4) The...

Embodiment 3

[0032] A western medicine combination for treating tetanus, which is composed of the following raw materials in parts by weight: 5 parts of norethindrone tablets, 1 part of ox horn, 10 parts of leflunomide powder, 4 parts of silkworm cocoon shells, 4 parts of shredded tobacco, 30 parts of normal saline, 0.5 parts of vitamin C, and 0.05 parts of vitamin C.

[0033] A preparation method of a western medicine combination for treating tetanus, the preparation method comprising:

[0034] (1) After cleaning, crushing and sterilizing the ox horns, sieve 70 meshes, mix the crushed ox horns with leflunomide powder, silkworm cocoon shells, and shredded tobacco, put them in a muffle furnace, and calcinate at 195°C for 8 minutes ;

[0035] (2) Pulverize the calcined coke-like product, then add physiological saline, vitamin C and powdered norethindrone tablets, and mix uniformly;

[0036] (3) Put the product obtained in step (2) into a rotary evaporator, and evaporate it at 102°C for 12 ...

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PUM

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Abstract

The invention discloses a western medicine combination for treatment of tetanus and a preparation method thereof. The western medicine combination is composed of, by weight, 3-7 parts of norethisterone tablets, 0.5-2 parts of ox horns, 8-15 parts of leflunomide powder, 2-5 parts of cocoon shells, 2-5 parts of tobacco shreds, 10-50 parts of normal saline and 0.01-0.1 part of vitamin C. Through the synergistic effect of raw material compounding, the western medicine combination has the effects of clearing away heat and toxic materials, diminishing inflammation and swelling and drawing out poison, and can restrain and kill the viability of clostridium tetani; in the therapeutic process, no complication is founded, and no obvious toxic and side effect occurs; the course of treatment is short, quick effect is achieved, the preparation method is simple, the production cost is low, the economic pressure of patients is lowered, the patients have no pains in the treatment process, and the taste is good; and clinical tests prove that the western medicine combination is safe and effective and can be used for treatment of tetanus.

Description

technical field [0001] The invention relates to the technical field of western medicine, in particular to a western medicine combination for treating tetanus and a preparation method thereof. Background technique [0002] Tetanus is an acute infectious disease characterized by muscle tonic spasms caused by Clostridium tetani invading human wounds, growing and multiplying in an anaerobic environment, producing neurotropic exotoxins and causing muscle tonic spasms throughout the body. Severe patients may die from laryngospasm or secondary severe lung infection. Neonatal tetanus is caused by infection of the umbilical cord and has a high case-fatality rate. Although the World Health Organization has actively promoted the global immunization program, it is estimated that there are still nearly one million tetanus cases in the world every year, and hundreds of thousands of newborns die of tetanus. The disability rate of tetanus is about 10%, and the treatment of tetanus usually...

Claims

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Application Information

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IPC IPC(8): A61K36/81A61P31/04A61P21/02A61K31/375A61K31/42A61K31/567A61K35/32A61K35/64
CPCA61K31/375A61K31/42A61K31/567A61K35/32A61K35/63A61K36/81A61K2300/00
Inventor 不公告发明人
Owner ZHENGZHOU ZHENGXIAN PHARMA CO LTD
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