Beam shaping body for neutron capture therapy

Abstract

The invention provides a beam shaping body for the neutron capture therapy. The beam shaping body comprises a beam inlet, a target material, a speed-retarding body adjacent to the target material, a reflector arranged to surround the outside of the speed-retarding body, a thermal neutron absorber adjacent to the speed-retarding body, a radiation shield arranged inside the beam shaping body, and a beam outlet. The nuclear reaction occurs between the target material and a proton beam that shoots into the beam inlet to generate neutrons, and the neutrons form a neutron beam which defines a main axis. The speed-retarding body slows down the neutrons generated from the target material to an epithermal neutron energy region. The speed-retarding body comprises the following materials of MgF2 and 6LiF, wherein the weight percentage of 6LiF to MgF2 is 0.1-5%. The above materials, in the form of powders or powder-pressed blanks, are subjected to powder sintering treatment by powder sintering equipment to turn into blocks. The reflector guides the neutrons deviating from the main axis back to the main axis so as to improve the intensity of an epithermal neutron beam. The thermal neutron absorber is used for absorbing thermal neutrons so as to avoid the excessive dose of the neutrons during the treatment on shallow normal tissues. The radiation shield is used for shielding leaky neutrons and photons so as to reduce the dose thereof on normal tissues in non-irradiated regions.

Description

technical field [0001] The invention relates to a beam shaping body, in particular to a beam shaping body for neutron capture therapy. Background technique [0002] With the development of atomic science, radiation therapy such as cobalt 60, linear accelerator, and electron beam has become one of the main means of cancer treatment. However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, traditional radiation therapy Treatment outcomes for more radiation-resistant malignancies (eg, glioblastoma multiforme, melanoma) are often poor. [0003] In order to reduce the radiation damage to normal tissues around the tumor, the concept of targeted therapy in chemotherapy (chemotherapy) has been applied to radiation therapy; and for tumor cells with...

AI Technical Summary

Problems solved by technology

However, traditional photon or electron therapy is limited by the physical conditions of the radiation itself. While killing tumor cells, it will also cause damage to a large number of normal tissues along the beam path; in addition, due to the different sensitivity of tumor cells to radiation, traditional radiation therapy Treatment of more radiation-resistant malignancies (eg, glioblastoma multiforme, melanoma) is often less effective

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