Method for utilizing radix astragali residues through liquid fermentation technology

A technology of liquid fermentation and medicinal residues, applied in the biological field, can solve the problems of environmental damage and waste of resources in the treatment method, and achieve the effect of high medicinal value

Inactive Publication Date: 2017-03-29
RINGPU TIANJIN BIOLOGICAL PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] With the development of the pharmaceutical industry, major Chinese medicine pharmaceutical companies have achieved good development, and the discharge of various types of Chinese medicine dregs is also increasing day by day. Buried and other treatment methods, such a treatment method not only destroys the environment, but also causes a waste of resources

Method used

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  • Method for utilizing radix astragali residues through liquid fermentation technology
  • Method for utilizing radix astragali residues through liquid fermentation technology

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] ⑴Select the dregs of Astragalus membranaceus, and accurately weigh 1 kg of the dregs of Astragalus membranaceus after drying;

[0022] (2) Add water with a mass of 4 kg of Radix Astragalus membranaceus dregs, stir continuously, decoct at 100°C for 30 minutes and filter, and decoct the filter residues in the same way to extract once more, and combine the two water extraction filtrates;

[0023] (3) concentrating under reduced pressure to a concentration of 0.2 g / mL of the water extract based on the weight of Astragalus medicinal residues;

[0024] ⑷ One of them is based on 1.0×10 4 The amount of cfu / mL was inoculated with Lactobacillus plantarum, and cultured at 30°C for 1 day;

[0025] (5) Filtration;

[0026] ⑹ It can be obtained by spray drying.

Embodiment 2

[0028] (1) Select astragalus powder dregs, and accurately weigh 1 kg of astragalus powder dregs after drying;

[0029] (2) Add 8 kg of water with the mass of astragalus powder and dregs, stir continuously, decoct at 100°C for 60 minutes and filter, and decoct the filter residue in the same way to extract once more, and combine the two times of water to extract the filtrate;

[0030] (3) Concentrate under reduced pressure to a concentration of 2 g / mL of the water extract based on the weight of Astragalus powder and dregs;

[0031] ⑷ One of them is based on 1.0×10 8 Inoculate Lactobacillus casei at the amount of cfu / mL, and culture at 40°C and 200rpm for 5 days;

[0032] (5) Filtration;

[0033] ⑹ It can be obtained by spray drying.

Embodiment 3

[0035] (1) Select the dregs of Astragalus decoction pieces, and accurately weigh 1 kg of the dregs of Astragalus decoction pieces after drying;

[0036] (2) Add 6 kg of water with the quality of the dregs of Astragalus decoction pieces, stir constantly, decoct at 100°C for 45 minutes, filter and filter, decoct the dregs in the same way to extract once more, and combine the two water extraction filtrates;

[0037] (3) Concentrate under reduced pressure until the concentration of the water extract based on the weight of the astragalus decoction pieces and dregs is 1 g / mL;

[0038] ⑷ One of them is based on 1.0×10 6 Lactobacillus acidophilus was inoculated with the amount of cfu / mL, and cultured at 37°C and 100rpm for 60 hours;

[0039] (5) Filtration;

[0040] ⑹ It can be obtained by spray drying.

[0041] Note: in the embodiment 1-3, two parts of Astragalus medicinal residues are selected, one part is inoculated with lactic acid bacteria (for the fermentation product group),...

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Abstract

The invention discloses a method for utilizing radix astragali residues through a liquid fermentation technology. The method mainly comprises the steps of (1) selecting radix astragali residues; (2) adding water of which the mass is 4 to 8 times that of radix astragali residues, continuously stirring the materials, and decocting the materials at the temperature of 100 DEG C; (3) carrying out decompression concentration; (4) inoculating the concentrate with lactic acid bacteria, and culturing lactic acid bacteria; (5) carrying out filtration; and (6) carrying out spray drying, so as to obtain a fermentation product. According to the method, radix astragali residues are dried through water extraction and can be in single body, decoction piece, powder, superfine powder forms, and the like, radix astragali residues are fermented through lactic acid bacteria like lactobacillus acidophilus, lactobacillus plantarum, enterococcus faecium, enterococcus faecalis and lactobacillus casei which are commonly utilized in the market or lactic acid bacteria separated from animal intestines, and the medicinal value of the fermentation liquor is improved.

Description

technical field [0001] The invention relates to a method for utilizing astragalus medicinal residues, in particular to a method for utilizing astragalus medicinal residues by liquid fermentation technology, and belongs to the field of biotechnology. Background technique [0002] Astragalus membranaceus is an important medicinal material in traditional Chinese pharmacy. At present, the medicinal Astragalus membranaceus stipulated in the Chinese Pharmacopoeia is the dried root of the leguminous plants Astragalus mongolica and Astragalus membranaceus. According to records, Astragalus membranaceus has the effects of invigorating qi and promoting yang, nourishing qi and strengthening the surface, promoting body fluid and quenching thirst, promoting detoxification and promoting muscle growth, and diuresis and swelling. The main active ingredients are astragalus polysaccharide, astragaloside IV, and astragalone. [0003] With the development of the pharmaceutical industry, major Ch...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/481
Inventor 高明燕李旭东刘爱玲陈光明王莹夏雪林
Owner RINGPU TIANJIN BIOLOGICAL PHARMA
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