Separation and extraction method for gentiopicroside in Picrorhiza scrophulariiflora Pennell

Abstract

Belonging to the technical field of chemical industry, the invention in particular relates to a separation and extraction method for gentiopicroside in Picrorhiza scrophulariiflora Pennell. The invention specifically employs extraction technique, macroporous resin column chromatography and silica gel column chromatography technique to elute a lot of gentiopicroside individually from a silica gel chromatographic column, thus increasing the extraction amount of gentiopicroside, and the finally obtained gentiopicroside has purity up to 98.7-99.3%, thus greatly improving the purity of gentiopicroside. The method provided by the invention has the advantages of wide application range, convenience and rapidity, low cost, simple operation and large separation amount, thereby being suitable for large-scale popularization and application.

Description

technical field

[0001] The invention belongs to the technical field of chemical industry, and in particular relates to a method for separating and extracting gentiopicroside from Tibet's rhizome. Background technique

[0002] Tibet Huhuanglian, also known as false Huhuanglian, is the dried rhizome of the perennial herb of the family Scrophulariaceae Huhuanglian. It is bitter in taste and cold in nature. It is an important medicinal material for clearing deficiency and heat. It has the functions of purging fire and detoxifying, and can be used for diseases such as bone steaming, labor heat, jaundice, cold and heat diarrhea, malnutrition in children, spontaneous sweating, night sweats, hemorrhoids, and sores. Studies have shown that the content of gentiopicroside in Tibetan Huhuanglian is relatively high. Gentiopicroside has anti-inflammatory, analgesic, hepatoprotective, and choleretic effects, and can be used to treat rheumatic joint pain, tuberculosis hot flashes, infantil...